Antibiotics

Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.

Showing 141-160 of 203 items.

Nigericin Sodium Salt

Catalog ID Size Pricing
N-650-10 10 mg $ 212.00
N-650-50 50 mg $ 747.00

Description

Nigericin is an ionophore antibiotic isolated from Streptomyces hygroscopicus. It has been shown to suppress DNA synthesis in Ehrlich ascites carcinoma. Nigericin is insoluble in water, but soluble in methanol and chloroform.

Nigericin sodium disrupts membrane potential by acting as an antiporter of H+ and K+ ions by exchanging K+ for H+. This causes a rapid decrease in intracellular pH.

Product Specifications

Catalog ID N-650
CAS # 28380-24-7
MW 746.94 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-650-10 10 mg $ 212.00
N-650-50 50 mg $ 747.00

Nisin

Catalog ID Size Pricing
N-660-1 1 g $ 62.00
N-660-5 5 g $ 165.00
N-660-25 25 g $ 578.00

Description

Nisin is a polypeptide antibiotic known as a lantibiotic. It has been isolated from Lactococcus lactis. Produced by gram-positive bacteria, the role of nisin is to reduce competitive strain due to the presence of other gram-positive bacteria.

Product Specifications

Catalog ID N-660
CAS # 1414-45-5
MW 3354.07 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-660-1 1 g $ 62.00
N-660-5 5 g $ 165.00
N-660-25 25 g $ 578.00

Nitrofurantoin, USP Grade

Catalog ID Size Pricing
N-690-100 100 g $ 186.00
N-690-250 250 g $ 255.00

Description

Nitrofurantoin is a bacteriostatic, nitrofuran antibiotic targeting gram-negative and gram-positive bacteria such as Enterococci, Staphylococci, Streptococci, Corynebacterium, and E. Coli. It has been used to study nitrofurantoin bacterial susceptibility and nitrofurantoin-induced toxicity. Additionally, it is a substrate for bacterial nitrofuran reductase.

Product Specifications

Catalog ID N-690
CAS # 67-20-9
MW 238.16 g/mol
Storage/Handling Store at 4°C. Protect from light.
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N-690-100 100 g $ 186.00
N-690-250 250 g $ 255.00

Norfloxacin

Catalog ID Size Pricing
N-700-5 5 g $ 82.00
N-700-10 10 g $ 145.00

Description

Norfloxacin is a first generation fluoroquinolone antibiotic targeting primarily gram-negative bacteria responsible for causing urinary tract infections. It is a derivative of pefloxacin.

Product Specifications

Catalog ID N-700
CAS # 70458-96-7
MW 319.33 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-700-5 5 g $ 82.00
N-700-10 10 g $ 145.00

Nourseothricin Sulfate (Streptothricin Sulfate) (NTC or clonNAT)

Catalog ID Size Pricing
N-500-100 100 mg $ 80.00
N-500-500 500 mg $ 214.00
N-500-1 1 g $ 313.00
N-500-2 2 x 1 g $ 574.00
N-500-3 3 x 1 g $ 821.00
N-500-4 4 x 1 g $ 1,047.00
N-500-5 5 x 1 g $ 1,246.00

Description

Nourseothricin is a broad-spectrum antibiotic derived from Streptomyces noursei. In addition to being effective on prokaryotic cells of gram-positive and gram-negative bacteria, various fungi including Candida albicans, and certain DNA and RNA viruses, it is also effective on eukaryotic cells of higher eukaryotes. It has been used as a selection agent for cells containing the gene conferring resistance to it.

GoldBio nourseothricin is a mixture of four streptothricin compounds: D and F (>85%) as well as C and E (<15%).

Product Specifications

Catalog ID N-500
CAS # 96736-11-7
MW Streptothricin D (758.86 g/mol), Streptothricin F (502.52 g/mol), Streptothricin E (630.69 g/mol), Streptothricin C (887.04 g/mol)
Storage/Handling Store desiccated at 4°C.
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N-500-100 100 mg $ 80.00
N-500-500 500 mg $ 214.00
N-500-1 1 g $ 313.00
N-500-2 2 x 1 g $ 574.00
N-500-3 3 x 1 g $ 821.00
N-500-4 4 x 1 g $ 1,047.00
N-500-5 5 x 1 g $ 1,246.00

Ofloxacin

Catalog ID Size Pricing
O-200-1 1 g $ 51.00
O-200-10 10 g $ 219.00

Description

Ofloxacin is a second generation fluoroquinolone antibiotic targeting gram-negative and gram-positive bacteria. It is an analog of nalidixic acid.

Product Specifications

Catalog ID O-200
CAS # 82419-36-1
MW 361.37 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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O-200-1 1 g $ 51.00
O-200-10 10 g $ 219.00

Oxolinic Acid

Catalog ID Size Pricing
O-300-5 5 g $ 126.00
O-300-25 25 g $ 426.00

Description

Oxolinic acid is a synthetic quinolone antibiotic targeting gram-negative bacteria, especially those responsible for causing urinary tract infections. It has also been reported to be effective against Burkholderia glumae, a bacteria causing grain rot, sheath rot, seedling rot, and bacterial panicle blight. It has been useful in studying transmissible resistance mechanisms of E. coli and S. enterica. It can be used to isolate Gardnerella vaginalis and as a dopamine reuptake inhibitor in neurological research.

Product Specifications

Catalog ID O-300
CAS # 14698-29-4
MW 261.23 g/mol
Grade MOLECULAR BIOLOGY GRADE
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O-300-5 5 g $ 126.00
O-300-25 25 g $ 426.00

Oxytetracycline

There is no image for Oxytetracycline Oxytetracycline
Catalog ID Size Pricing
O-600-500 500 g $ 149.00
O-600-1 1 kg $ 235.00
O-600-2.5 2.5 kg $ 445.00
O-600-5 5 kg $ 739.00
O-600-10 10 kg $ 925.00

Description

Oxytetracycline is a tetracycline antibiotic derived from Streptomyces rimosus. It targets gram-positive and gram-negative bacteria and several Mycoplasma species. Oxytetracycline has been used to study its resistance gene, otrA and in fluorescence analysis of liver cells.

Additionally, oxytetracycline is used as a selective agent in OGYE, a selective medium for yeasts and molds. It has been used to prevent fire blight in apples and pears and has been shown to be a better alternative to streptomycin against fire blight disease.

Product Specifications

Catalog ID O-600
CAS # 79-57-2
MW 460.43 g/mol
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O-600-500 500 g $ 149.00
O-600-1 1 kg $ 235.00
O-600-2.5 2.5 kg $ 445.00
O-600-5 5 kg $ 739.00
O-600-10 10 kg $ 925.00

Oxytetracycline Dihydrate

Catalog ID Size Pricing
O-400-10 10 g $ 57.00
O-400-50 50 g $ 284.00

Description

Oxytetracycline is a tetracycline antibiotic derived from Streptomyces rimosus. It targets gram-positive and gram-negative bacteria and several Mycoplasma species. Oxytetracycline has been used to study its resistance gene, otrA and in fluorescence analysis of liver cells.

Additionally, oxytetracycline is used as a selective agent in OGYE, a selective medium for yeasts and molds. It has been used to prevent fire blight in apples and pears and has been shown to be a better alternative to streptomycin against fire blight disease.

Product Specifications

Catalog ID O-400
CAS # 6153-64-6
MW 496.46 g/mol
Grade MOLECULAR BIOLOGY GRADE
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O-400-10 10 g $ 57.00
O-400-50 50 g $ 284.00

Oxytetracycline HCl

Catalog ID Size Pricing
O-410-10 10 g $ 50.00
O-410-50 50 g $ 117.00
O-410-100 100 g $ 197.00

Description

Oxytetracycline is a tetracycline antibiotic derived from Streptomyces rimosus. It targets gram-positive and gram-negative bacteria and several Mycoplasma species. Oxytetracycline has been used to study its resistance gene, otrA and in fluorescence analysis of liver cells.

Additionally, oxytetracycline is used as a selective agent in OGYE, a selective medium for yeasts and molds. It has been used to prevent fire blight in apples and pears and has been shown to be a better alternative to streptomycin against fire blight disease.

Product Specifications

Catalog ID O-410
CAS # 2058-46-0
MW 496.89 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store under inert gas at <4°C.
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O-410-10 10 g $ 50.00
O-410-50 50 g $ 117.00
O-410-100 100 g $ 197.00

Paromomycin Sulfate, USP Grade

Catalog ID Size Pricing
P-700-5 5 g $ 61.00
P-700-25 25 g $ 129.00
P-700-100 100 g $ 259.00

Description

Paromomycin is an aminoglycoside antibiotic isolated from Streptomyces rimosus. It targets a variety of gram-negative and gram-positive bacteria as well as several protozoan species. It displays activity similar to that of neomycin. Paromomycin sulfate is freely soluble.

Product Specifications

Catalog ID P-700
CAS # 1263-89-4
MW 713.71 g/mol
Storage/Handling Store at 4°C.
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P-700-5 5 g $ 61.00
P-700-25 25 g $ 129.00
P-700-100 100 g $ 259.00

Pefloxacin Mesylate Dihydrate

Catalog ID Size Pricing
P-710-10 10 g $ 69.00
P-710-50 50 g $ 276.00

Description

Perfloxacin is a fluoroquinolone antibiotic and is an analog of norfloxacin. It targets gram-negative and gram-positive bacteria as well as several Mycoplasma species. It is commonly used against Gonococcal species and to induce achilles tendon toxicity in rodents.

Product Specifications

Catalog ID P-710
CAS # 149676-40-4
MW 465.49 g/mol
Grade MOLECULAR BIOLOGY GRADE
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P-710-10 10 g $ 69.00
P-710-50 50 g $ 276.00

Penicillin G Potassium Salt, USP Grade

Catalog ID Size Pricing
P-303-50 50 g $ 45.00
P-303-100 100 g $ 65.00
P-303-1 1 kg $ 385.00

Description

Penicillin G is a β-lactam antibiotic produced by the Penicillium fungus. It has shown efficacy against a variety of Streptococcus species as well as non-penicillinase producing Staphylococcus species. The potassium salt is useful in studying Staphylococcus murosomes and Streptococcus mutans. This product has been tested against both sensitive and resistant cells.

Product Specifications

Catalog ID P-303
CAS # 113-98-4
MW 372.48 g/mol
Grade USP GRADE
Storage/Handling Store desiccated at -20°C.
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P-303-50 50 g $ 45.00
P-303-100 100 g $ 65.00
P-303-1 1 kg $ 385.00

Penicillin G Sodium Salt, USP Grade

Catalog ID Size Pricing
P-304-50 50 g $ 45.00
P-304-100 100 g $ 69.00

Description

Penicillin G is a β-lactam antibiotic produced by the Penicillium fungus. It has shown efficacy against a variety of Streptococcus species as well as non-penicillinase producing Staphylococcus species.

Product Specifications

Catalog ID P-304
CAS # 69-57-8
MW 356.37 g/mol
Grade USP GRADE
Storage/Handling Store desiccated at -20°C.
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P-304-50 50 g $ 45.00
P-304-100 100 g $ 69.00

Pipemidic Acid

Catalog ID Size Pricing
P-720-10 10 g $ 85.00
P-720-100 100 g $ 533.00

Description

Pipemidic acid is a pyridopyrimidine antibiotic with similar properties to quinolone antibiotics. It is used to study damage and mutations in DNA as well as lymphocyte blastogenesis and interferon-gamma production. It can be used as a cell selection agent.

Product Specifications

Catalog ID P-720
CAS # 51940-44-4
MW 303.32 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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P-720-10 10 g $ 85.00
P-720-100 100 g $ 533.00

Piperacillin

Catalog ID Size Pricing
P-730-500 500 mg $ 90.00
P-730-1 1 g $ 127.00

Description

Piperacillin is an extended-spectrum β-lactam antibiotic resistant to many β-lactamases. It is derived from ampicillin and targets gram-negative and gram-positive bacteria. Additionally, piperacillin has been used in studies on optimization of antimicrobial therapy in patients with sepsis and to study piperacillin allergic reactions. It has also been used to study multidrug resistant organisms.

Product Specifications

Catalog ID P-730
CAS # 61477-96-1
MW 517.55 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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P-730-500 500 mg $ 90.00
P-730-1 1 g $ 127.00

Piperacillin Sodium

Catalog ID Size Pricing
P-733-1 1 g $ 98.00
P-733-5 5 g $ 390.00
P-733-10 10 g $ 539.00

Description

Piperacillin is an extended-spectrum β-lactam antibiotic resistant to many β-lactamases. It is derived from ampicillin and targets gram-negative and gram-positive bacteria. Additionally, piperacillin has been used in studies on optimization of antimicrobial therapy in patients with sepsis and to study piperacillin allergic reactions. It has also been used to study multidrug resistant organisms.

Product Specifications

Catalog ID P-733
CAS # 59703-84-3
MW 539.54 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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P-733-1 1 g $ 98.00
P-733-5 5 g $ 390.00
P-733-10 10 g $ 539.00

Polymyxin B Sulfate

Catalog ID Size Pricing
P-740-10 10 MU $ 134.00
P-740-100 100 MU $ 518.00

Description

Polymyxin B sulfate is a polypeptide antibiotic mixture of B1, B2, and B3 polymyxins. Each of these fractions vary by a fatty acid group and exhibit marginal MIC differences when compared. Polymyxin B is most effective against gram-negative bacteria. It has been shown to work against Pseudomonas aeruginosa, Pseudomonas viridiflava, and Erwinia carotovora. Polymyxin B is freely soluble in aqueous solution.

Product Specifications

Catalog ID P-740
CAS # 1405-20-5
MW 1385.61 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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P-740-10 10 MU $ 134.00
P-740-100 100 MU $ 518.00

Puromycin Dihydrochloride

Catalog ID Size Pricing
P-600-100 100 mg $ 99.00
P-600-500 500 mg $ 345.00
P-600-1 1 g $ 609.00

Description

Puromycin is an aminonucleoside antibiotic that causes early chain termination within the ribosome during translation. This inhibition of translation is effective in both in vivo and in vitro applications, making it an ideal tool for protein synthesis studies. While selection for E. coli cells is possible with puromycin, it is more commonly and effectively used for mammalian cell selection.

The growth of bacteria, protozoa, algae and mammalian cells is quickly halted by puromycin. However, cells with the pac gene have resistance. Its gene product is puromycin-N-acetyl-transferase which inactivates puromycin through acetylation.

Research has shown puromycin to be effective against certain tumors.

Product Specifications

Catalog ID P-600
CAS # 58-58-2
MW 544.43 g/mol
Storage/Handling Store desiccated at -20°C.
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P-600-100 100 mg $ 99.00
P-600-500 500 mg $ 345.00
P-600-1 1 g $ 609.00

Pyrazinamide

Catalog ID Size Pricing
P-770-25 25 g $ 76.00
P-770-100 100 g $ 241.00

Description

Pyrazinamide is an anti-tubercular antibiotic. It is also used to study ways to prevent liver toxicity and in the formation of polymeric copper complexes.

Although the mechanism of action of pyrazinamide is not well understood, it is thought that upon entering a target cell, it is converted to pyrazinoic acid or POA. This conversion results in altered cellular permeability and decreased internal pH due to POA accumulation in the cytoplasm. This may inhibit fatty acid synthesis.

Product Specifications

Catalog ID P-770
CAS # 98-96-4
MW 123.11 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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P-770-25 25 g $ 76.00
P-770-100 100 g $ 241.00

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