D_Products

A unique combination of a number of proprietary plasmids digested with appropriate restriction enzymes and PCR products to yield 13 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 250-10,000 base pairs. The 1K and 3K bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 μg a load) for approximating the mass of DNA in comparably intense samples. The ladder is ready-to-use, and is premixed with loading buffer dye for direct loading on gel.

The 1 kb PLUS™ is composed of 14 individual DNA fragments: 25K, 10K, 8K, 6K, 5K, 4K, 3K, 2.5K, 2K, 1500, 1000, 750, 500, 250 base pairs. This product contains two enhanced bands (3K and 1K bp) for easy reference. The ladder is ready-to-use, and is premixed with loading buffer dye for direct loading on gel.

1,2-Di-O-tetradecyl-sn-glycerol is a reagent for chemical synthesis.

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a phospholipid found in eukaryotes, but not most bacteria. It is used in lipid bilayer studies to analyze organelle and cell membranes. It’s also been used to study molecules in membranes, such as the interaction between DMPC and proteins in lab-constructed dimyristoylphosphatidylcholine vesicles.

1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) is a lipid found in the cell membranes of bacteria and human nervous tissues. DMPE membranes are more viscous than phosphatidylcholine. It is assumed that due to the oxidative stress placed on cells from phosphatidylethanolamine-linked products that their presence in foods is responsible for diseases like cancer and diabetes.

1,2-Dipalmitoyl-rac-glycero-3-phosphocholine is a phospholipid with two palmitic acids and is the racemic mixture of Dipalmitoylphosphatidylcholine (also known as Colfosceril palmitate or DPPC). The phosphocholine head is sensitive to electric charges at the membrane surface when bound to pure phospholipids. When added to a solution containing charged ions, this sensitivity can shift the nitrogen cation away from a lack of positive charge or towards a positive charge in solution. In a research environment, it is useful in studying changes of biological membranes and liposomes. Because of its ability to form simple phospholipid bilayers, it is useful in computer modeling of bilayers in dynamic situations. Modeling can also be extended to interactions between DPPC and other biologically active molecules (like pharmaceuticals) as an analog for the same naturally occurring process. It is also useful in the formation of reconstituted HDL particles.

1,2-Dipalmitoyl-rac-glycero-3-phosphoethanolamine is a phospholipid and reagent used in chemical synthesis.

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine or DPPE is a phospholipid component of the cell membrane. It is used in membrane models and is part of the glycerophosphoethanolamine family. DPPE has been shown to cause competitive hydrogen bonding of amine groups with phosphate/carbonyl groups or water. Additionally, DPPE has been studied along with cholesterol, showing cholesterol’s ability to induce DPPE monolayer condensation when calcium ions are present.

1,2:5,6-Di-O-isopropylidene-alpha-D-glucofuranose is a reagent used for chemical synthesis. 1,2:5,6-Di-O-isopropylidene-alpha-D-glucofuranose (or diacetone-D-glucose (DAG)) can be used to create racemically pure alkane- and arenesulfinyl chlorides with a tertiary amine. Oxidation and reduction can lead to an allofuranose derivative.

1,3-Diphenylacetone is a reagent in many chemical synthesis applications.

10-Deacetyl baccatin III is an intermediate in the synthesis of the chemotherapeutic drug, paclitaxel (taxol). It is produced by and isolated from Taxus baccata. 10-Deacetyl baccatin III is an immiscible organic compound.

A unique combination of PCR products and a number of proprietary plasmids digested with appropriate restriction enzymes to yield 11 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 100-1,500 base pairs. The 500 and 1,500 base pair bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 μg a load) for approximating the mass of DNA in comparably intense samples of similar size. The ladder is ready-to-use, and is premixed with loading buffer dye for direct loading on gel.

A unique combination of PCR products and a number of proprietary plasmids digested with appropriate restriction enzymes to yield 12 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 100-3,000 base pairs. The 500 and 1,500 base pair bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 μg a load) for approximating the mass of DNA in comparably intense samples of similar size.The ladder is ready-to-use, and is premixed with loading buffer dye for direct loading on gel.

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) has a variety of applications. DDQ is a deprotection agent for ketals, acetals, and thioacetals. It is a useful electron transfer reagent for synthesis of quinolones and an oxidizing agent used to synthesize steroids. Additionally, DDQ is used with Ph3P to synthesize 1,2-benzisoxazoles.

2,3-Dimethylindole is a reagent used in chemical synthesis. As a cyclic indole it is used in creation of agonists and Bis(indolyl)methane derivatives, and in general Diels-Alder and electron transfer reactions. It is used to study properties of other indoles, and possesses chemiluminescence properties when reacted with peroxides.

2,4-Dihydroxybenzoic acid is a resorcylic acid with a large number of applications. It possesses antioxidant, anti-radical and hydrogen peroxide scavenging. It also has potential as a wastewater treatment when activated with ultrasound. As a reagent it has been used to synthesize mycophenolic acid, protein 90 inhibitors and pde4 inhibitors.

2,5-Dichloropyridine is a reagent used in chemical synthesis. It has been used to synthesize 4-benzodiazepine-2,5 diones as Hdm2 antagonists and inhibitors of ERK protein kinase.

2-Deoxy-D-galactose is a deoxy hexose that inhibits synthesis of glycoproteins in Influenza virus, such as hemagglutinin and neuraminidase, by blocking glycosylation. 2-Deoxy-D-galactose also inhibits the glycosylation of mammalian proteins involved in neurotransmitter release and synaptogenesis in the hippocampus. It has been used for isolating galactose permease mutants of Salmonella typhimurium and in the inhibition of glycolysis in Saccharomyces cerevisiae. It has also been used to isolate and elucidate the activity of a system for galactose uptake into E. coli.

2-Deoxy-D-glucose is a molecule with a broad range of applications, from a reagent to a potential anti-cancer drug. As a reagent it can be combined with the radiolabel fluorine-18 to monitor glucose metabolism using positron emission tomography (PET) allowing detection of altered metabolism resulting from diseases like Alzheimer’s and cardiovascular disease. As a therapeutic drug 2-Deoxy-D-glucose uptake is the same as regular glucose, but has an inhibiting effect on cell growth. This makes it an effective tumor suppressant. It is a potential anti-epileptic drug due to its mimicry of ketogenic diets used for treating epilepsy, by increasing Brain-derived neurotrophic factors, nerve and basic fibroblast growth factors and Arc protein. 2-Deoxy-D-glucose’s anti-cancer properties stem from its ability to slow both tumor growth and mark tissues with elevated glucose and hexokinase activity, which are common markers for cancer activity. It can also be used to increase the absorption of other chemotherapy agents like adriamycin and paclitaxel.