B_Products

(+)-Bicuculline, a light-sensitive competitive GABAA and GABAA-gated chloride channel antagonist, functions in the biochemical field as a drug, CNS stimulator, convulsant and neurotransmitter. Its chemical identities are alkaloid and phthalide-isoquinoline compound. Extracted from plant alkaloid in 1932, this metabolite has been definitively located in Adlumia fungosa, Dicentra cucullaria, Fumariaceae and some species of Corydalis. (+)-Bicuculline acts primarily on ionotropic GABAA receptors but also blocks Ca2+-activated potassium channels and can act as an agrochemical.

As a poisonous neurotoxin, it affects nervous system responses associated with GABAA by binding to the receptors but not activating them, thus inhibiting the action of gamma-aminobutyric acid. This produces a powerful convulsive reaction mimicking epilepsy and has been used in lab studies of the condition. Administered with NMDA, it has induced paraplegia. Injection to the amygdala has also produced GABA-related anxiolytic effects on emotional states.

1,2-Benzoisothiazolin-3-one, sodium salt is an isothiazolinone biocine used in plants and as a preservative. Its mode of action is both fungicidal and microbicidal.

2,2’-Bipyridine is a metalloprotease inhibitor used as a reagent for the colorimetric determination of iron. It is a base used for oxidation-reductions indicators and to confirm the presence of ferrous iron in soils. Additionally, 2,2’-bipyridine is used in transition metal catalysis and aluminum-initiated polymerization. It is a high-affinity iron chelator and may inhibit iron-containing enzymes.

28-homo-brassinolide is a plant hormone from a class of polyhydroxysteroids that has been shown to have a protective role in plants under various stress situations; showing significant improvement of plant growth, water uptake, photosynthesis and yield. 28-homo-brassinolide has been shown to be the most effective of any of the brassinosteroids in mitigating plant stress effects from natural conditions such as chilling, drought, heat or salinity.

Brassinosteriods are a group of plant hormones that occur naturally in the plant kingdom. They have a variety of physiological roles including cell division and elongation, gene regulation, photosynthesis, senescence, enzyme activation and growth.

4,6-Benzylidene-4-nitrophenyl-alpha-D-maltoheptaoside is a reagent used for chemical synthesis.

4-(Benzyloxy)aniline is used as a building block for biochemical synthesis.

4-Benzyloxyindole is a reactant in a variety of preparation procedures. It is used in the synthesis of 4-aryl-4H-chromenes as an inducer of apoptosis, in the synthesis of indol-3-yl tetramethylcyclopropyl ketones as a CB2 cannabinoid receptor ligand, and in the synthesis of hepatitis C inhibitors. Additionally, 4-Benzyloxyindole is used to prepare carbon-11-labeled-4-aryl-4H-chromenes as PET agents in cancer studies, to prepare indoles through Bartoli reductive cyclization, and to synthesize oxopyrrolidine analogs in iodine-catalyzed Markovnikov additions.

4-Benzyloxyindole-2-carboxylic acid ethyl ester is a reagent for building organic molecules.

4-Bromoindole is studied for its potential use as a GSK-3 inhibitor.

5-Benzyloxy-DL-tryptophan is a reagent used in chemical synthesis.

5-Benzyloxyindole is a useful chemical reagent. It is used in preparation of indole and quinoline carbothioic acid amide derivatives. It is also used in various Friedel-Crafts alkylation reactions as well as specific C-3 alkenylation reactions and preparation of protein kinase (PKC) inhibitors.

5-Benzyloxyindole-2-carboxylic acid is a cyclic reagent for the synthesis of organic molecules. It’s used as a reagent in the synthesis of histamine 3 receptor antagonists and PPAR-γ binding agents.

Can be used as a substrate for carboxyl esterase, yielding a blue precipitate upon cleavage.

5-Bromo-4-chloro-3-indoxyl octanoate; X-caprylate

5-Bromo-4-chloro-3-indoxyl nonanoate is a chromogenic substrate that yields a blue precipitate with C9 cleavage.

5-Bromo-4-chloro-3-indoxyl phosphate is used in visualizing alkaline phosphatase activity via immunohistochemistry. It is also used as a substrate and visualizing agent in blotting, ELISA’s and in situ hybridization.

5-Bromo-4-chloro-3-indoxyl thymidine-3'-phosphate is an enzyme substrate for phosphodiesterase II and can also be used for detecting bacterial deoxyribonuclease. It yields a blue precipitate.