Carbapenems
Carbapenems are a class of β-lactams with broad antibacterial activity. β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes that catalyze a pentaglycine cross-link between alanine and lysine residues, providing additional strength to the cell wall. Without a pentaglycine cross-link, the integrity of the cell wall is severely compromised, and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Carbapenems are highly resistant to β-lactamases, and are commonly used as a last resort antibiotic of choice in the medical field due to their broad efficacy against both gram-positive and gram-negative bacteria and their poor oral bioavailabilility.
Showing 1-2 of 2 items.
Faropenem Sodium
| Catalog ID | Size | Pricing | |
|---|---|---|---|
| F-350-50 | 50 mg | $ 296.00 |
Description
Faropenem sodium is an ultra broad-spectrum β-lactam of the penem antibiotic class. It has been shown to be β-lactamase resistant and is especially effective against anaerobic bacteria responsible for oral infections, but targets a variety of gram-positive and gram-negative bacteria. Faropenem sodium is freely soluble in water.
Product Specifications
| Catalog ID | F-350 |
|---|---|
| CAS # | 122547-49-3 |
| MW | 307.30 g/mol |
| Grade | MOLECULAR BIOLOGY GRADE |
Meropenem
| Catalog ID | Size | Pricing | |
|---|---|---|---|
| M-820-10 | 10 g | $ 285.00 |
Description
Meropenem is a carbapenem β-lactam antibiotic. It targets gram-negative and gram-positive bacteria and displays high resistance to β-lactamase and kidney dehydropeptidase I activity. It is especially effective against bacteria responsible for causing meningitis and exhibits low toxicity when compared to similar antibiotics.
Product Specifications
| Catalog ID | M-820 |
|---|---|
| CAS # | 119478-56-7 |
| MW | 437.51 g/mol |
| Storage/Handling | Store desiccated at -20°C. |
