Antibiotics

Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.

Showing 161-180 of 203 items.

Rapamycin

Catalog ID Size Pricing
R-101-25 25mg $ 49.00
R-101-100 100 mg $ 175.00
R-101-500 500 mg $ 779.00

Description

Rapamycin is a macrolide antibiotic isolated from Streptomyces hygroscopicus. It has been shown to display anticancer activity such as induction of apoptosis and inhibition of angiogenesis and proliferation in tumor cell lines. Rapamycin is also an immunosuppressant and FRAP inhibitor and inhibits lymphokine-induced cell proliferation.

Product Specifications

Catalog ID R-101
CAS # 53123-88-9
MW 914.17 g/mol
Storage/Handling Store at room temperature.
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R-101-25 25mg $ 49.00
R-101-100 100 mg $ 175.00
R-101-500 500 mg $ 779.00

Ribostamycin Sulfate

Catalog ID Size Pricing
R-400-250 250 mg $ 303.00
R-400-1 1 g $ 664.00

Description

Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosifidicus. It is a broad-spectrum antibiotic targeting gram-positive and gram-negative bacteria. Ribostamycin has been used to in pharmacokinetic studies and to study kidney toxicity. It is also an inhibitor of protein disulfide isomerase (PDI).

Product Specifications

Catalog ID R-400
CAS # 53797-35-6
MW 552.55 g/mol
Grade MOLECULAR BIOLOGY GRADE
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R-400-250 250 mg $ 303.00
R-400-1 1 g $ 664.00

Rifampicin, Molecular Biology Grade

Catalog ID Size Pricing
R-120-1 1 g $ 39.00
R-120-5 5 g $ 75.00
R-120-10 10 g $ 119.00
R-120-25 25 g $ 195.00
R-120-50 50 g $ 315.00

Description

Rifampicin is a broad-spectrum antibiotic known for its efficacy against tuberculosis and other infections caused by Mycobacterium species. This semisynthetic antibiotic has also been shown to work against methicillin-resistant Staphylococcus aureus (MRSA), to activate nuclear pregnane x receptor (PXR), and to promote CYP2C-mediated metabolism.

Rifampicin functions by binding the β-subunit of RNA polymerase, inhibiting RNA synthesis. Resistance to this antibiotic develops from mutations on the binding site on RNA polymerase leading to a lower affinity for rifampicin.

Product Specifications

Catalog ID R-120
CAS # 13292-46-1
MW 822.94 g/mol
Storage/Handling Store desiccated at -20°C.
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R-120-1 1 g $ 39.00
R-120-5 5 g $ 75.00
R-120-10 10 g $ 119.00
R-120-25 25 g $ 195.00
R-120-50 50 g $ 315.00

Roxithromycin

Catalog ID Size Pricing
R-500-5 5 g $ 71.00
R-500-10 10 g $ 129.00

Description

Roxithromycin is a macrolide antibiotic and derivative of erythromycin. It targets both gram-negative and gram-positive bacteria and has shown strong efficacy against Legionella pneumophila and a variety of oral pathogens. Additionally, roxithromycin inhibits the activation of NADPH oxidase and promotes neutrophil apoptosis.

Product Specifications

Catalog ID R-500
CAS # 80214-83-1
MW 837.05 g/mol
Grade MOLECULAR BIOLOGY GRADE
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R-500-5 5 g $ 71.00
R-500-10 10 g $ 129.00

Salinomycin

Catalog ID Size Pricing
S-200-5 5 mg $ 191.00
S-200-25 25 mg $ 624.00

Description

Salinomycin is a coccidiostat ionophore antibiotic isolated from Streptomyces albus. It increases cation movement across cell membranes through exchange-diffusion, resulting in altered gradients due to a lack of control of ion permeability. This effect allows ions (K+, Na+, Ca+, Mg2+) to accumulate inside the cell, reaching toxic levels.

Product Specifications

Catalog ID S-200
CAS # 53003-10-4
MW 751.00 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-200-5 5 mg $ 191.00
S-200-25 25 mg $ 624.00

Salinomycin Sodium

Catalog ID Size Pricing
S-210-50 50 mg $ 101.00
S-210-100 100 mg $ 169.00
S-210-1 1 g $ 275.00

Description

Salinomycin is a coccidiostat ionophore antibiotic isolated from Streptomyces albus. It increases cation movement across cell membranes through exchange-diffusion, resulting in altered gradients due to a lack of control of ion permeability. This effect allows ions (K+, Na+, Ca+, Mg2+) to accumulate inside the cell, reaching toxic levels. Salinomycin sodium is freely soluble in aqueous solution.

Product Specifications

Catalog ID S-210
CAS # 55721-31-8
MW 772.98 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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S-210-50 50 mg $ 101.00
S-210-100 100 mg $ 169.00
S-210-1 1 g $ 275.00

Sarafloxacin HCl Trihydrate

Catalog ID Size Pricing
S-300-5 5 g $ 62.00
S-300-25 25 g $ 193.00

Description

Sarafloxacin is a broad-spectrum fluoroquinolone antibiotic effective against a variety of gram-negative and gram-positive organisms, especially Mycobacterium tuberculosis. Sarafloxacin HCl Trihydrate is water soluble.

Product Specifications

Catalog ID S-300
CAS # 91296-87-6 (anhydrous)
MW 475.87 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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S-300-5 5 g $ 62.00
S-300-25 25 g $ 193.00

Sisomicin Sulfate

Catalog ID Size Pricing
S-350-500 500 mg $ 151.00
S-350-1 1 g $ 264.00

Description

Sisomicin is a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. It is related to gentamicin and targets gram-negative and gram-positive bacteria such as Klebsiella species, E. coli, P. aeruginosa, Enterobacter species, and Proteus species. It has been used in disk and tube dilution sensitivity assays.

Product Specifications

Catalog ID S-350
CAS # 53179-09-2
MW 692.72 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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S-350-500 500 mg $ 151.00
S-350-1 1 g $ 264.00

Sparfloxacin

Catalog ID Size Pricing
S-460-10 10 g $ 157.00

Description

Sparfloxacin is a broad-spectrum fluoroquinolone antibiotic targeting gram-negative and gram-positive bacteria as well as Mycoplasma species. It is especially effective against bacteria responsible for respiratory tract infections such as pneumonia. Sparfloxacin also displays photosensitizing effects.

Product Specifications

Catalog ID S-460
CAS # 110871-86-8
MW 392.40 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-460-10 10 g $ 157.00

Spectinomycin Dihydrochloride Pentahydrate 100 mg/mL Solution

Catalog ID Size Pricing
S-140-SL10 10 mL $ 59.00
S-140-SL25 25 mL $ 85.00
S-140-SL50 50 mL $ 115.00
S-140-SL100 100 mL $ 145.00

Description

Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.

Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID S-140-SL
CAS # 22189-32-8
MW 495.35 g/mol
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S-140-SL10 10 mL $ 59.00
S-140-SL25 25 mL $ 85.00
S-140-SL50 50 mL $ 115.00
S-140-SL100 100 mL $ 145.00

Spectinomycin Dihydrochloride Pentahydrate EZ Pak™ for 100 mg/mL Solution

Catalog ID Size Pricing
S-140-EZ25 25 mL $ 59.00
S-140-EZ50 50 mL $ 85.00
S-140-EZ100 100 mL $ 115.00

Description

The Spectinomycin Dihydrochloride Pentahydrate EZ Pak™ is the fastest and easiest way to make a set amount of sterile spectimomycin dihydrochloride solution. The kit includes pre-weighed spectimomycin dihydrochloride powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H2O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high quality GoldBio spectimomycin dihydrochloride and the sterile solution is ready for tissue culture, bacterial media or any number of uses.

Product Specifications

Catalog ID S-140-EZ
CAS # 22189-32-8
MW 495.35 g/mol
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S-140-EZ25 25 mL $ 59.00
S-140-EZ50 50 mL $ 85.00
S-140-EZ100 100 mL $ 115.00

Spectinomycin Dihydrochloride Pentahydrate, USP Grade

Catalog ID Size Pricing
S-140-5 5 g $ 39.00
S-140-25 25 g $ 115.00
S-140-50 50 g $ 189.00
S-140-250 250 g $ 795.00

Description

Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.

Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.

Product Specifications

Catalog ID S-140
CAS # 22189-32-8
MW 495.35 g/mol
Storage/Handling Store desiccated at -20°C.
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S-140-5 5 g $ 39.00
S-140-25 25 g $ 115.00
S-140-50 50 g $ 189.00
S-140-250 250 g $ 795.00

Spiramycin

Catalog ID Size Pricing
S-470-1 1 g $ 90.00
S-470-5 5 g $ 313.00

Description

Spiramycin is a broad-spectrum macrolide antibiotic effective against gram-negative and gram-positive bacteria as well as some Toxoplasma parasites. Spiramycin is a mixture of spiramycin I, II, and III and has been used to study sepsis in mice.

Product Specifications

Catalog ID S-470
CAS # 8025-81-8
MW 843.05 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-470-1 1 g $ 90.00
S-470-5 5 g $ 313.00

Streptomycin Sulfate

Catalog ID Size Pricing
S-150-50 50 g $ 29.00
S-150-100 100 g $ 45.00

Description

Streptomycin is an aminoglycoside antibiotic primarily effective against gram-negative bacteria and Mycobacterium species. It is commonly used in cell culture media to prevent bacterial contamination. It has also been used to precipitate nucleic acids during protein purification techniques and to study mechanisms of Streptomycin resistance.

Product Specifications

Catalog ID S-150
CAS # 3810-74-0
MW 1457.40 g/mol
Storage/Handling Store desiccated at -20°C.
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S-150-50 50 g $ 29.00
S-150-100 100 g $ 45.00

Streptomycin Sulfate 100 mg/mL Solution

Catalog ID Size Pricing
S-150-SL10 10 mL $ 45.00
S-150-SL25 25 mL $ 75.00
S-150-SL50 50 mL $ 105.00
S-150-SL100 100 mL $ 145.00

Description

Streptomycin is an aminoglycoside antibiotic primarily effective against gram-negative bacteria and Mycobacterium species. It is commonly used in cell culture media to prevent bacterial contamination. It has also been used to precipitate nucleic acids during protein purification techniques and to study mechanisms of Streptomycin resistance.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID S-150-SL
CAS # 3810-74-0
MW 1457.40 g/mol
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S-150-SL10 10 mL $ 45.00
S-150-SL25 25 mL $ 75.00
S-150-SL50 50 mL $ 105.00
S-150-SL100 100 mL $ 145.00

Streptomycin Sulfate EZ Pak™ for 100 mg/mL Solution

Catalog ID Size Pricing
S-150-EZ10 10 mL $ 45.00
S-150-EZ25 25 mL $ 75.00
S-150-EZ50 50 mL $ 105.00
S-150-EZ100 100 mL $ 145.00

Description

The Streptomycin Sulfate EZ Pak™ is the fastest and easiest way to make a set amount of sterile streptomycin sulfate solution. The kit includes pre-weighed streptomycin sulfate powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H2O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high-quality GoldBio streptomycin sulfate, and the sterile solution is ready for tissue culture, bacterial media or any number of uses.

Product Specifications

Catalog ID S-150-EZ
CAS # 3810-74-0
MW 1457.40 g/mol
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S-150-EZ10 10 mL $ 45.00
S-150-EZ25 25 mL $ 75.00
S-150-EZ50 50 mL $ 105.00
S-150-EZ100 100 mL $ 145.00

Sulbactam

Catalog ID Size Pricing
S-500-10 10 mg $ 76.00
S-500-50 50 mg $ 338.00

Description

Sulbactam is a β-lactamase inhibitor useful in combination with β-lactam antibiotics to increase their potency. It irreversibly inactivates β-lactamase enzymes, preventing them from degrading β-lactam antibiotics. Sulbactam has been used in combination with ampicillin and cefoperazone to inhibit β-lactamase enzymes during Agrobacterium-mediated plant genetic modifications. It may also be used in cell signaling studies.

Product Specifications

Catalog ID S-500
CAS # 68373-14-8
MW 233.24 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-500-10 10 mg $ 76.00
S-500-50 50 mg $ 338.00

Sulbactam Sodium

Catalog ID Size Pricing
S-501-10 10 mg $ 73.00
S-501-500 500 mg $ 138.00

Description

Sulbactam is a β-lactamase inhibitor useful in combination with β-lactam antibiotics to increase their potency. It irreversibly inactivates β-lactamase enzymes, preventing them from degrading β-lactam antibiotics. Sulbactam has been used in combination with ampicillin and cefoperazone to inhibit β-lactamase enzymes during Agrobacterium-mediated plant genetic modifications. It may also be used in cell signaling studies. Sulbactam sodium is freely soluble in aqueous solution.

Product Specifications

Catalog ID S-501
CAS # 69388-84-7
MW 255.22 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-501-10 10 mg $ 73.00
S-501-500 500 mg $ 138.00

Sulfadoxine (Sulphadoxine)

Catalog ID Size Pricing
S-550-10 10 g $ 81.00
S-550-25 25 g $ 186.00

Description

Sulfadoxine is a broad-spectrum sulfonamide antibiotic effective against gram-negative and gram-positive bacteria. It is commonly used against malaria, especially Plasmodium falciparum malaria with chloroquine resistance. It has been used to study Toxoplasma gondii infections and to prevent infections in post-surgical animal models.

Product Specifications

Catalog ID S-550
CAS # 2447-57-6
MW 310.33 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-550-10 10 g $ 81.00
S-550-25 25 g $ 186.00

Sulfamethazine

Catalog ID Size Pricing
S-610-100 100 g $ 72.00

Description

Sulfamethazine is broad-spectrum sulfonamide antibiotic targeting bacteria causing bronchitis and urinary tract infections. It is used in disposition and depletion studies of kinetics and to develop procedures used for quantification. Sulfamethazine is also an inducer of CYP3A4.

Product Specifications

Catalog ID S-610
CAS # 57-68-1
MW 278.33 g/mol
Grade MOLECULAR BIOLOGY GRADE
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S-610-100 100 g $ 72.00

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