R_Products

Showing 1-20 of 104 items.

Basic FGF (FGF2), Rat

Catalog ID Size Pricing
1540-02-10 10 μg $ 101.00
1540-02-100 100 μg $ 308.00
1540-02-500 500 μg $ 647.00

Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Fibroblast Growth Factor 2
Fibroblast Growth Factor-basic
bFGF, FGF-2
basic FGF

FGF2 is a member of the Fibroblast Growth Factor family of proteins. It is often called FGF-basic or bFGF. FGF2 is a single-chain polypeptide growth factor that plays a significant role in wound healing, it is a potent inducer of angiogenesis and it is essential for the growth of many stem and progenitor cells. FGF2 shares a 55% amino acid residue identity with FGF1 and interacts with heparin sulfate with nanomolar affinity. It is a potent inducer of DNA synthesis in a variety of cell types. FGF2 activates mesenchymal splice variants of FGF receptors (c splice variants) and also activates FGF Receptor 1b, but has little activity against FGFR2b or FGFR3b. It is most closely associated with FGF1 (aFGF) (see additional information).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

Product Specifications

Catalog ID 1540-02
MW ~16.3 kDa
Storage/Handling Store desiccated at -20°C.
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1540-02-10 10 μg $ 101.00
1540-02-100 100 μg $ 308.00
1540-02-500 500 μg $ 647.00

CCL11, Rat

Catalog ID Size Pricing
2540-11-5 5 μg $ 101.00

Description

Rat CCL11 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in fibroblasts, epithelial cells, smooth muscle cells, and dendritic cells. Expression of CCL11 is upregulated by several proinflammatory cytokines, including IL1A and TNFA, and is inhibited by IFNG. CCL11 is strongly and selectively chemotactic and activating for eosinophils and is involved in a variety of eosinophilic inflammatory diseases. It also plays a role in angiogenesis and tumor growth. CCL11 is a ligand primarily for CCR3, but also CCR1, CCR2, CCR5, and ACKR2 (D6).

Product Specifications

Catalog ID 2540-11
MW ~8.4 kDa
Storage/Handling Store desiccated at -20°C.
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2540-11-5 5 μg $ 101.00

CCL11, Rhesus Macaque

Catalog ID Size Pricing
2240-11-5 5 μg $ 101.00

Description

CCL11 is a chemokine containing four conserved cysteine residues, the first two of which are adjacent. It is expressed in dermal fibroblasts. Expression of CCL11 is induced by IL1A and TNFA and inhibited by IFNG. It is strongly and selectively chemotactic for eosinophils and induces a calcium flux response in eosinophils. CCL11 induces angiogenesis and endothelial cell sprouting from aortic rings in the absence of an eosinophil and has been implicated to be involved in a variety of eosinophilic inflammatory diseases. CCL11 is a ligand for CCR1, CCR2, CCR3, CCR5, and ACKR2 (D6).


GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Product Specifications

Catalog ID 2240-11
MW ~8.4 kDa
Storage/Handling Store desiccated at -20°C.
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2240-11-5 5 μg $ 101.00

CCL17, Rat

Catalog ID Size Pricing
2540-17-5 5 μg $ 101.00

Description

Rat CCL17 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed constitutively in the thymus and lymph nodes and transiently in peripheral blood mononuclear cells that have been induced by phytogemagglutinin. CCL17 is chemotactic for T-cells and plays a role in T-cell development, trafficking, and activation. It promotes atherosclerosis by regulating homeostasis of regulatory T-cells, thereby limiting their expansion. CCL17 is a ligand for CCR4, CCR8, and the erythrocyte receptor ACKR1.

Product Specifications

Catalog ID 2540-17
MW ~8.1 kDa
Storage/Handling Store desiccated at -20°C.
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2540-17-5 5 μg $ 101.00

CCL22, Rat

There is no image for CCL22, Rat CCL22, Rat
Catalog ID Size Pricing
2540-22-5 5 μg $ 101.00

Description

Rat CCL22 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in activated splenic B-cells, macrophages, and dendritic cells. Expression of CCL22 is induced by IL4, IL13, and IFNG and inhibited by IL10. Increased expression CCL22 has also been observed after incubation of mast cells with TNF-alpha or IgE. CCL22 is chemotactic for chronically activated T-cells and plays a role in trafficking activated T cells. It also plays a role in migration and survival of cells expressing FOXP3. CCL22 is a ligand for CCR4.

Product Specifications

Catalog ID 2540-22
MW ~7.9 kDa
Storage/Handling Store desiccated at -20°C.
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2540-22-5 5 μg $ 101.00

CCL24, Rat

Catalog ID Size Pricing
2540-24-5 5 μg $ 101.00

Description

Rat CCL24 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed by activated monocytes and activated T lymphocytes. CCL24 is expressed in jejunum and spleen constitutively and is upregulated by allergen challenge and IL4 overexpression. CCL24 is chemotactic for resting T lymphocytes and eosinophils and is a suppressor of HPP-CFC myeloid progenitor cells. It causes a transient rise in intracellular calcium levels in eosinophils and is involved in a variety of eosinophilic inflammatory diseases. CCL24 is a ligand for CCR3.

Product Specifications

Catalog ID 2540-24
MW ~10.5 kDa
Storage/Handling Store desiccated at -20°C.
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2540-24-5 5 μg $ 101.00

CCL28, Rat

There is no image for CCL28, Rat CCL28, Rat
Catalog ID Size Pricing
2540-28-5 5 μg $ 101.00

Description

Rat CCL28 is a chemokine containing six conserved cysteine residues, two of which are adjacent. It is expressed constitutively in epithelial cells at mucosal sites, such as salivary glands and the colon, and expression is upregulated by proinflammatory stimuli such as IL1 and n-butyrate. CCL28 is chemotactic for resting T-cells, eosinophils, and IgA antibody-secreting cells (ASCs). It is important for regulating IgA ASC accumulation in mammary glands and consequently the transfer of IgA antibodies from mother to infant. CCL28 displays antimicrobial activity in low-salt conditions against Candida albicans, gram-negative, and gram positive bacteria. CCL28 is a ligand for CCR10 and CCR3.

Product Specifications

Catalog ID 2540-28
MW ~13.1 kDa
Storage/Handling Store desiccated at -20°C.
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2540-28-5 5 μg $ 101.00

CCL3, Rat

Catalog ID Size Pricing
2540-03-5 5 μg $ 101.00

Description

No description available

Product Specifications

Catalog ID 2540-03
MW ~7.9 kDa
Storage/Handling Store desiccated at -20°C.
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2540-03-5 5 μg $ 101.00

CCL4, Rat

Catalog ID Size Pricing
2540-04-5 5 μg $ 101.00

Description

Rat CCL4 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed and secreted by T-cells, B-cells, monocytes, and various tumor cells lines. Expression of CCL4 is induced by IL2 and mitogens, such as phytohemmagglutinin, LPS, and the peptidoglycan wall of S. aureus and expression is inhibited by glucocorticoids, TGF-beta, and cyclosporin A. CCL4 is an HIV-suppressive factor and may contribute to amyloid deposition in Alzheimer disease. It also binds to HSV-1 virions and generates pores in the envelope of HSV-1. CCL4 is a ligand for CCR1, CCR3, CCR5, CCR8, and ACKR2 (D6).

Product Specifications

Catalog ID 2540-04
MW ~7.8 kDa
Storage/Handling Store desiccated at -20°C.
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2540-04-5 5 μg $ 101.00

CCL6, Rat

There is no image for CCL6, Rat CCL6, Rat
Catalog ID Size Pricing
2540-06-10 10 μg $ 149.00

Description

Rat CCL6 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed primarily in microglia and other macrophages, as well as myelopoietic bone marrow cells. Upregulation of expression of CCL6 has been observed after stimulation with IFNG, CSF1, CSF2, IL3, and IL4. CCL6 expression is also stimulated by IL-13 and is required for IL-13 stimulation of other chemokines. CCL6 is chemotactic for macrophages and lymphocytes and acts as a ligand primarily for CCR1. CCL6 has only been observed in rodents thus far; rat CCL6 is most homologous to human CCL14, CCL15, and CCL23.

Product Specifications

Catalog ID 2540-06
MW ~10.4 kDa
Storage/Handling Store desiccated at -20°C.
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2540-06-10 10 μg $ 149.00

CCL7, Rat

There is no image for CCL7, Rat CCL7, Rat
Catalog ID Size Pricing
2540-07-10 10 μg $ 149.00

Description

Rat CCL7 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It was first isolated from murine mast cells stimulated by IgE interacting with an antigen and is expressed and secreted by T cells, monocytes, macrophages, and a variety of tumor cell lines. Expression is induced by IFNG and inhibited by IL13. It is chemotactic for monocytes, macrophages, eosinophils, and NK cells and regulates protease secretion by macrophages which may contribute to metastasis of cancer cells. CCL7 also promotes neuritogenesis in midbrain dopamine neuron cultures. CCL7 is a ligand primarily for CCR2, as well as CCR1, CCR3, CCR10, and ACKR2 (D6).

Product Specifications

Catalog ID 2540-07
MW ~8.5 kDa
Storage/Handling Store desiccated at -20°C.
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2540-07-10 10 μg $ 149.00

CDNF, Rat

Catalog ID Size Pricing
1570-16-5 5 μg $ 101.00

Description

CDNF is a secreted neurotrophic factor that contains 8 conserved cysteine residues, much like its relative MANF. CDNF and its structural homolog MANF each contain an N-terminal saposin-like lipid binding domain and a carboxyl-terminal domain, which is not homologous to previously characterized protein structures. CDNF is expressed in several tissues, including the embryonic and postnatal brains of mice, as well as the heart, skeletal muscle, and testis. It has been shown to promote survival, growth and function of dopamine specific neurons. CDNF and MANF can prevent 6-OHDA induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson disease.

Product Specifications

Catalog ID 1570-16
MW ~18.8 kDa
Storage/Handling Store desiccated at -20°C.
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1570-16-5 5 μg $ 101.00

Cellulase R-10

There is no image for Cellulase R-10 Cellulase R-10
Catalog ID Size Pricing
C8001.0001 1 g $ 93.00
C8001.0005 5 g $ 200.00
C8001.0010 10 g $ 286.00

Description

Cellulase R-10, also called Cellulase "Onozuka" R-10, is derived from Trichoderma Viride. Cellulase R-10 is a multi-enzymatic system consisting of various enzymes, including cellulase, hemicellulase, pectinase and protease. Cellulase R-10 is typically used in association with macerozyme R-10 in the decomposition of plant cell walls to produce protoplasts.

Product Specifications

Catalog ID C8001
CAS # 9012-54-8
Storage/Handling Store at room temperature.
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C8001.0001 1 g $ 93.00
C8001.0005 5 g $ 200.00
C8001.0010 10 g $ 286.00

Cellulase RS

There is no image for Cellulase RS Cellulase RS
Catalog ID Size Pricing
C8003.0001 1 g $ 141.00
C8003.0005 5 g $ 403.00
C8003.0010 10 g $ 636.00

Description

Cellulase “Onozuka RS” is produced by a mutant Trichoderma viride that was derived from the parent strain for Cellulase “Onozuka -R-10”. Cellulase RS contains a very high activity of decomposing natural celluloses. This type of cellulase can be used to obtain protoplasts in a very short time and dissolves cell walls of a wider range of plants.

Product Specifications

Catalog ID C8003
CAS # 9012-54-8
Storage/Handling Store desiccated at 4°C.
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C8003.0001 1 g $ 141.00
C8003.0005 5 g $ 403.00
C8003.0010 10 g $ 636.00

CNTF, Rat

Catalog ID Size Pricing
1570-08-5 5 μg $ 101.00
1570-08-100 100 μg $ 674.00
1570-08-500 500 μg $ 1,394.00

Description

Ciliary neurotrophic factor (CNTF) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. It was initially identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. The protein is also a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition, CNTF is useful for treatment of motor neuron disease and it could reduce food intake without causing hunger or stress. CNTF is structurally related to IL6, IL11, LIF, and OSM. All of these four helix bundle cytokines share gp130 as a signal-transducing subunit in their receptor complexes.

Product Specifications

Catalog ID 1570-08
MW ~22.7 kDa
Storage/Handling Store desiccated at -20°C.
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1570-08-5 5 μg $ 101.00
1570-08-100 100 μg $ 674.00
1570-08-500 500 μg $ 1,394.00

Competent Cell Recovery Medium

Catalog ID Size Pricing
CC-300-A 6 x 12 ml $ 80.00

Description

GoldBio’s Competent Cell Recovery Medium has a superior formulation recommended for all competent cell transformation. Our Recovery Medium is formulated to achieve the highest possible transformation efficiency from any competent cell.

  • Achieve the highest possible transformation efficiency from any competent cell
  • Enhanced SOC formulation provided with all of Intact Genomics’ competent cells
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CC-300-A 6 x 12 ml $ 80.00

Coomassie Brilliant Blue R-250

Catalog ID Size Pricing
C-461-5 5 g $ 30.00
C-461-25 25 g $ 43.00
C-461-100 100 g $ 80.00

Description

Coomassie Brilliant Blue R-250 (CBBR) is a member of the Coomassie family and is used extensively as an analytical dye in SDS-PAGE.

Product Specifications

Catalog ID C-461
CAS # 6104-59-2
MW 825.97 g/mol
Storage/Handling Store desiccated at room temperature.
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C-461-5 5 g $ 30.00
C-461-25 25 g $ 43.00
C-461-100 100 g $ 80.00

Cresol red

There is no image for Cresol red Cresol red
Catalog ID Size Pricing
C-830-10 10 g $ 40.00
C-830-25 25 g $ 80.00
C-830-50 50 g $ 125.00
C-830-100 100 g $ 200.00
C-830-250 250 g $ 400.00

Description

Cresol red is a color marker and pH indicator for various laboratory procedures. As a color marker in agarose and polyacrylamide electrophoresis at 1% it runs at 125 base pair size, and as a titrant indicator Cresol Red is yellow below pH 7.2 and purple at pH 8.8 and above. Cresol Red can be used with Taq polymerase because it does not inhibit reactions unlike other dyes and has also been used as a pH sensitive optical fiber sensor.

Product Specifications

Catalog ID C-830
CAS # 1733-12-6
MW 382.43 g/mol
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C-830-10 10 g $ 40.00
C-830-25 25 g $ 80.00
C-830-50 50 g $ 125.00
C-830-100 100 g $ 200.00
C-830-250 250 g $ 400.00

CSF2 (GM-CSF), Rat

Catalog ID Size Pricing
1520-03-5 5 μg $ 101.00
1520-03-100 100 μg $ 716.00
1520-03-500 500 μg $ 1,474.00

Description

Colony Stimulating Factor 2 (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts, in response to cytokine or immune and inflammatory stimuli. On mature hematopoietic cells, CSF2 is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils. CSF2 promotes a Th1 biased immune response, angiogenesis, allergic inflammation and the development of autoimmunity. It shows clinical effectiveness in ameliorating chemotherapy-induced neutropenia, and CSF2 transfected tumor cells are utilized as cancer vaccines. Mature rat CSF2 shares 69% with mouse CSF2. Rat CSF2 is fully active on mouse cells, although Mouse CSF2 is only weakly active on rat cells.

Product Specifications

Catalog ID 1520-03
MW ~14.5 kDa
Storage/Handling Store desiccated at -20°C.
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1520-03-5 5 μg $ 101.00
1520-03-100 100 μg $ 716.00
1520-03-500 500 μg $ 1,474.00

CSF2 (GM-CSF), Rhesus macaque

Catalog ID Size Pricing
1220-03-10 10 μg $ 149.00
1220-03-100 100 μg $ 1,182.00
1220-03-500 500 μg $ 2,295.00

Description

Colony Stimulating Factor 2 (CSF2), previously called Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF), is secreted by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation. It was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors and has functions of stimulates the growth and differentiation of hematopoietic precursor cells from various lineages. CSF2 has also been reported to have a functional role on non-hematopoietic cells and can induce human endothelial cells to migrate and proliferate. Additionally, it can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. It is reported that CSF2 has no biological effects across species.

Product Specifications

Catalog ID 1220-03
MW ~14.4 kDa
Storage/Handling Store desiccated at -20°C.
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1220-03-10 10 μg $ 149.00
1220-03-100 100 μg $ 1,182.00
1220-03-500 500 μg $ 2,295.00

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