A_Products

(-)-Arctigenin is a dibenzylbutyrolactone ligand found in the root of Arctium lappa L. It is an inhibitor of topoisomerase II, viral integrase including HIV-1 integrase, PAC-1, TNF-alpha, and nitric oxide secretion. Additionally, (-)-arctigenin displays anti-oxidative, anti-inflammatory, and anti-cancer properties. (-)-Arctigenin has been used in research on cosmetics and pharmaceutical products.

2-Amino-1-phenylethanol is an amine with a structure similar to neurotransmitters like dopamine.

2-Amino-4,6-dichloropyrimidine is a reagent used for pyrimidine synthesis. Pyrazolo pyrimidines can be synthesized via microwaves under solvent free conditions, and can be used to create Anti-HIV carbocyclic 2,6 Disubstituted purine nucleosides.

2-Amino-4-chlorobenzoic acid is a substituted benzoic acid. It can form complexes with yttrium and certain lanthanides, and as a reagent in the creation of metal complexes.

2-Amino-4-fluorobenzoic acid is a substituted benzoic acid. It has been used in the synthesis of benzothiazole derivatives used for cervical cancers, and as a reagent in the synthesis of other anti-infective agents.

2-Aminoisobutyric acid is researched for its use in the prediction of type 2 diabetes. As a component in the alanine cycle, 2-aminoisobutyric acid contributes to the regulation of alanine aminotransferases making it useful in diabetes diagnostics.

3-Acetylindole is a substituted indole and a reactant in the first step of multiple biological synthesis applications. Indoles, especially 3-acetylindole derivatives, possess a wide variety of biological activities. Many biological molecules, from Antibacterial agents against Staphylococcus to anti-HIV synthesis agents like N-arylsulfonyl-3-acetylindoles, use 3-acetylindole as a starting reagent. They can react with aromatic aldehydes to produce chalcones, which are intermediates for biologically active heterocyclic compounds. 3-Acetylindole is also the reactant for the synthesis of inhibitors that are used with hepatitis protease and nuclear factor kappa-light-chain enhancer of B cells (NF-κB).

Agarose is a very inert polysaccharide that forms hydrophilic and high gel strength gels at low concentrations.
Agarose beads are microspheres of agarose gels with different particle diameters and concentrations. Small spherical particles of agarose act as a porous gel to filter or separate a mixture of molecules according to their individual sizes. Due to its chemical structure (easy to activate), the agarose beads may be prepared to bind biomolecules in a reversible or irreversible manner. Plain agarose beads are used in gel filtration chromatography (or molecular exclusion chromatography) as well as for activating beads for biomolecule purification or immobilization.
Plain agarose beads can also be used for activating processes, generating active groups inside its pores capable of reversible or irreversible biomolecule bonds. Due to the bead’s large internal surface and to its composition (inert polysaccharide), agarose is an ideal medium for the preparation of activated beads.

Agarose is a very inert polysaccharide that forms hydrophilic and high gel strength gels at low concentrations.
Agarose beads are microspheres of agarose gels with different particle diameters and concentrations. Small spherical particles of agarose act as a porous gel to filter or separate a mixture of molecules according to their individual sizes. Due to its chemical structure (easy to activate), the agarose beads may be prepared to bind biomolecules in a reversible or irreversible manner.
Cross-linked agarose beads are used in gel filtration chromatography (or molecular exclusion chromatography) as well as for activating beads for biomolecule purification or immobilization.
Cross-linked agarose beads can also be used for activating processes, generating active groups inside its pores capable of reversible or irreversible biomolecule bonds. Due to the bead’s large internal surface and to its composition (inert polysaccharide), agarose is an ideal medium for the preparation of activated beads.

This matrix is a highly cross-linked 4% agarose bead with a bead size of 50-150 µm. It is a gel filtration resin developed for industrial-scale separation of large molecules and virus particles utilizing higher pressure and flow rates rather than low pressure standard beads.

This matrix is not preactivated. For preactivated resins, look for Glyoxal Agarose Beads or Protein G.

4-Acetoxyindole is an indole with an acetyl group. It is used as a starting reactant in the preparation of 4-oxoquinoline, which is used as an anti-HIV agent. In chromatography it is used to help optimize peak capacity for the separation of low molecular weight molecules during gradient elution.

P-aminophenyl phosphate (pAPP) can be used as a substrate for alkaline phosphatase enzymatic reactions in order to electrochemically quantify ALP activity.

The enzymatic reaction results in the production of phenol, which can be quantified and used to analyze ALP concentrations.

ALP is a naturally occurring enzyme and can be found in human tissue in the liver, bone and intestines. Usual concentrations of ALP range between 25-100 IU/L. A significant spike outside of that range could act as a signal for many diseases.

4-Aminophenyl-β-D-galactopyranoside is a substrate for β-galactosidase. It is also a weak β-D-galactosidase inducer and can be used in affinity chromatography for isolation of galactose-binding. The 4-aminophenyl releases upon cleavage by β-galactosidase. It can then be assayed by electro-oxidation to 4-imino quinone while recording changes in the potential or current galvanic system.

4-Azaindole is used a reagent for the creation of complex molecules. When combined with a bisalkoxyalkyl spacer, they can be used to target melatonin MT 1 receptors over MT 2 receptors.

5-Amino-2-nitrobenzoic acid is a reagent used in preparation of polymer-bound diazonium salts and insulin receptor tyrosine kinase activator. It is also used in 2-component dendritic chain reactions and activation of hydrophobic dendrimers.

5-Aminogramine is an antagonistic gramine derivative of 5-Hydroxytryptamine.

5-Aminoindole is used in a variety of preparation applications. It is used to prepare cytotoxic and antimitotic agents, HIV protease inhibitors, PCKθ inhibitors, IGF-1 receptor inhibitors, anticancer agents, antivascular agents, tyrosine kinase receptor inhibitors, and Smac mimetics binding the XIAP apoptosis-inhibiting protein.

5-Aminoisophthalic acid is used in proteomics research.

5-Aminolevulinic acid hexyl ester is used in many fluorescence applications to detect cancer cells (such as bladder cancer) and protoporphyrin IX(PpIX) product that can be seen in photodetection.