Nisin is a polypeptide antibiotic known as a lantibiotic. It has been isolated from Lactococcus lactis. Produced by gram-positive bacteria, the role of nisin is to reduce competitive strain due to the presence of other gram-positive bacteria.
When it comes in contact with other gram-positive bacteria, nisin creates pores in the cell membrane leading to loss of membrane permeability control. This ultimately leads to cell lysis and death. Nisin is not effective on gram-negative organisms, but is effective against a wide variety of gram-positive bacteria. It has been used as a selection agent to isolate gram-negative bacteria, yeast, and molds. It has also been used to study post-translational modification.
MOLECULAR BIOLOGY GRADE
MW: 3,354.07 g/mol
Storage/Handling: Store at 2-8°C.
PubChem Chemical ID: 16219761
|Grade||MOLECULAR BIOLOGY GRADE|
|Storage/Handling||Store at 4°C.|