Nalidixic acid

Nalidixic acid is a naphthyridone antibiotic that is similar in structure and mechanism to quinolones and is effective against both gram-positive and gram-negative bacteria. It acts as a bacteriostatic in lower concentrations but can be bacteriocidal at higher concentrations. Nalidixic acid indirectly inhibits proteins synthesis by binding DNA and interfering with enzymes involved in DNA replication and transcription.

Nalidixic acid is freely soluble in methylene chloride, slightly soluble in water and is commonly used as a selective agent in many isolation medias; including Columbia Blood Agar and Fraser Broth.

Product Specifications
Nalidixic Acid;
1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid

MOLECULAR BIOLOGY GRADE

C₁₂H₁₂N₂O₃

MW: 232.24 g/mol

PubChem CID: 4421

Storage/Handling: Store at 4°C.
Soluble in methylene chloride and methanol. Slightly soluble in aqueous solutions (0.1 mg/ml).