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Showing 1-20 of 186 items.

1,2-O-Isopropylidene-sn-glycerol

There is no image for 1,2-O-Isopropylidene-sn-glycerol 1,2-O-Isopropylidene-sn-glycerol
Catalog ID Size Pricing
I-890-25 25 g $ 72.00
I-890-50 50 g $ 122.00
I-890-100 100 g $ 236.00
I-890-250 250 g $ 572.00
I-890-500 500 g $ 1,111.00

Description

1,2-O-Isopropylidene-sn-glycerol is a reagent used in chemical synthesis. It is used in the preparation of tetraoxaspiroundecanes, diglycerides and glyceryl phosphates.

Product Specifications

Catalog ID I-890
CAS # 22323-82-6
MW 132.16 g/mol
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I-890-25 2-3 Weeks 25 g $ 72.00
I-890-50 2-3 Weeks 50 g $ 122.00
I-890-100 2-3 Weeks 100 g $ 236.00
I-890-250 2-3 Weeks 250 g $ 572.00
I-890-500 2-3 Weeks 500 g $ 1,111.00

2,3-O-Isopropylidene-sn-glycerol

There is no image for 2,3-O-Isopropylidene-sn-glycerol 2,3-O-Isopropylidene-sn-glycerol
Catalog ID Size Pricing
I-840-25 25 g $ 96.00
I-840-50 50 g $ 179.00
I-840-100 100 g $ 345.00
I-840-250 250 g $ 833.00

Description

2,3-O-Isopropylidene-sn-glycerol is a reagent used in chemical synthesis. It is used in the preparation of tetraoxaspiroundecanes, diglycerides and glyceryl phosphates.

Product Specifications

Catalog ID I-840
CAS # 14347-78-5
MW 132.16 g/mol
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I-840-25 2-3 Weeks 25 g $ 96.00
I-840-50 2-3 Weeks 50 g $ 179.00
I-840-100 2-3 Weeks 100 g $ 345.00
I-840-250 2-3 Weeks 250 g $ 833.00

3-Indoxyl caprylate

There is no image for 3-Indoxyl caprylate 3-Indoxyl caprylate
Catalog ID Size Pricing
I-510-500 500 mg $ 438.00

Description

3-Indoxyl caprylate is a reagent used in chemical synthesis.

Product Specifications

Catalog ID I-510
CAS # 133950-66-0
MW 259.34 g/mol
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I-510-500 2-3 Weeks 500 mg $ 438.00

3-Indoxyl phosphate bis (2-amino-2-methyl-1,3-propanediol) salt

Catalog ID Size Pricing
I-490-50 50 mg $ 84.00
I-490-500 500 mg $ 519.00
I-490-1 1 g $ 588.00

Description

3-Indoxyl phosphate bis (2-amino-2-methyl- 1,3-propanediol) salt
Y™-phosphate bis(2-amino-2-methyl-1,3-propanediol) salt
Y™-phos • 2 AMPD

Product Specifications

Catalog ID I-490
CAS # 107475-12-7
MW 423.41 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at -20°C. Protect from light.
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I-490-50 2-3 Weeks 50 mg $ 84.00
I-490-500 2-3 Weeks 500 mg $ 519.00
I-490-1 2-3 Weeks 1 g $ 588.00

3-Indoxyl-1,3-diacetate

There is no image for 3-Indoxyl-1,3-diacetate 3-Indoxyl-1,3-diacetate
Catalog ID Size Pricing
I-550-25 25 g $ 637.00

Description

3-Indoxyl-1,3-diacetate is a reagent used in the synthesis of chromogenic substrates.

Product Specifications

Catalog ID I-550
CAS # 16800-67-2
MW 217.22 g/mol
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I-550-25 2-3 Weeks 25 g $ 637.00

3-Indoxyl-3-acetate

Catalog ID Size Pricing
I-425-10 10 g $ 276.00
I-425-25 25 g $ 632.00
I-425-50 50 g $ 1,199.00

Description

3-Indoxyl-3-acetate is a chromogenic substrate used to differentiate between esterases of various microorganism species.

Product Specifications

Catalog ID I-425
CAS # 608-08-2
MW 175.19 g/mol
Storage/Handling Store at -20°C. Protect from light.
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I-425-10 2-3 Weeks 10 g $ 276.00
I-425-25 2-3 Weeks 25 g $ 632.00
I-425-50 2-3 Weeks 50 g $ 1,199.00

3-Iodo-L-tyrosine

Catalog ID Size Pricing
I-540-5 5 g $ 99.00
I-540-10 10 g $ 178.00
I-540-25 25 g $ 421.00
I-540-50 50 g $ 702.00

Description

3-Iodo-L-tyrosine is a tyrosine hydroxylase inhibitor.

Product Specifications

Catalog ID I-540
CAS # 70-78-0
MW 307.09 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C. Protect from light.
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I-540-5 2-3 Weeks 5 g $ 99.00
I-540-10 2-3 Weeks 10 g $ 178.00
I-540-25 In stock 25 g $ 421.00
I-540-50 2-3 Weeks 50 g $ 702.00

4-Isothiocyanatophenyl-alpha-D-mannopyranoside

Catalog ID Size Pricing
I-120-10 10 mg $ 85.00
I-120-25 25 mg $ 170.00
I-120-50 50 mg $ 304.00
I-120-100 100 mg $ 499.00
I-120-250 250 mg $ 829.00

Description

4-Isothiocyanatophenyl-alpha-D-mannopyranoside is an organic isothiocyanate compound used in carbohydrate chemistry. It is a building block and reagent which is used for preparing neoglycoproteins. This solid powder carbohydrate melts at 179-182°C. β-D-mannoside is a component of this molecule.

The incorporation of the N=C=S chemical group qualifies 4-Isothiocyanatophenyl-alpha-D-mannopyranoside as an isothiocyanate, a molecule group which frequently appears in food and medical sciences. This compound type produces an assortment of related flavors in vegetables. In coordination chemistry, isothiocyanates can operate as ligands.

Product Specifications

Catalog ID I-120
CAS # 96345-79-8
MW 313.33 g/mol
Storage/Handling Store desiccated at 4°C.
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I-120-10 2-3 Weeks 10 mg $ 85.00
I-120-25 2-3 Weeks 25 mg $ 170.00
I-120-50 2-3 Weeks 50 mg $ 304.00
I-120-100 2-3 Weeks 100 mg $ 499.00
I-120-250 2-3 Weeks 250 mg $ 829.00

5,6-O-Isopropylidene-L-gulono-1,4-lactone

There is no image for 5,6-O-Isopropylidene-L-gulono-1,4-lactone 5,6-O-Isopropylidene-L-gulono-1,4-lactone
Catalog ID Size Pricing
I-770-1 1 g $ 95.00
I-770-2 2 g $ 175.00
I-770-5 5 g $ 320.00
I-770-10 10 g $ 494.00
I-770-25 25 g $ 872.00

Description

5,6-O-Isopropylidene-L-gulono-1,4-lactone is a reagent for chemical synthesis.

Product Specifications

Catalog ID I-770
CAS # 94697-68-4
MW 218.20 g/mol
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I-770-1 2-3 Weeks 1 g $ 95.00
I-770-2 2-3 Weeks 2 g $ 175.00
I-770-5 2-3 Weeks 5 g $ 320.00
I-770-10 2-3 Weeks 10 g $ 494.00
I-770-25 2-3 Weeks 25 g $ 872.00

5X Phosphate Buffer + 3M Imidazole Solution

Catalog ID Size Pricing
I-905-100 100 mL $ 225.00

Description

This Buffer Set consists of:

- 5X Phosphate Buffer, pH8 (250 mM Phosphate buffer pH 8, 1.5 M NaCl)
- 25 mL 3M Recrystallized Imidazole Solution, pH 6.0

This Buffer set allows researchers to develop, wash and elute buffers for His-tag protein purification.

Product Specifications

Catalog ID I-905
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I-905-100 In stock 100 mL $ 225.00

DL-Indole-3-lactic acid

There is no image for DL-Indole-3-lactic acid DL-Indole-3-lactic acid
Catalog ID Size Pricing
I-360-1 1 g $ 425.00

Description

DL-Indole-3-lactic acid is a reagent used in chemical synthesis. It is one of the building blocks of the sweetener Monatin and Fab I inhibitors. It is a tryptophan metabolite of Bifidobacterium.

Product Specifications

Catalog ID I-360
CAS # 832-97-3
MW 205.21 g/mol
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I-360-1 2-3 Weeks 1 g $ 425.00

IAA (Indole-3-Acetic Acid)

Catalog ID Size Pricing
I-110-25 25 g $ 45.00
I-110-100 100 g $ 95.00
I-110-500 500 g $ 329.00
I-110-1 1 kg $ 555.00
I-110-2.5 2.5 kg $ 1,339.00
I-110-5 5 kg $ 2,425.00

Description

IAA (Indole-3-Acetic Acid) is the abundant and well known plant hormone of the auxin class. IAA is predominantly produced in the apical bud of and young leaves of plants and is known to be an inducer of cell division and elongation. IAA, as well as most other auxins, are also known to act in concert with, or in opposition to, other plant hormones. For example, the ratio of auxin to cytokinin in certain plant tissues determines initiation of root versus shoot buds.

Product Specifications

Catalog ID I-110
CAS # 87-51-4
MW 175.18 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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I-110-25 In stock 25 g $ 45.00
I-110-100 In stock 100 g $ 95.00
I-110-500 In stock 500 g $ 329.00
I-110-1 In stock 1 kg $ 555.00
I-110-2.5 In stock 2.5 kg $ 1,339.00
I-110-5 In stock 5 kg $ 2,425.00

IBA (Indole-3-butyric acid)

Catalog ID Size Pricing
I-180-5G 5 g $ 29.00
I-180-50 50 g $ 69.00
I-180-250 250 g $ 215.00
I-180-500 500 g $ 349.00
I-180-1 1 kg $ 645.00
I-180-2.5 2.5 kg $ 1,525.00

Description

IBA (Indole-3-butyric acid) is a plant hormone belonging to the auxin family and assists in initiating root formation; the in vitro process is called micropropagation. Aside from accelerating root formation, it is used on various crops to stimulate flower development and the growth of fruits. This ultimately increases crop yields.

Historically, products that contained IBA were used to protect plants during transplantation by stimulating root growth and decreasing shock.

Product Specifications

Catalog ID I-180
CAS # 133-32-4
MW 203.24 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
UN Number 2811
Item Class 6.1
Group Number III
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I-180-5G In stock 5 g $ 29.00
I-180-50 In stock 50 g $ 69.00
I-180-250 In stock 250 g $ 215.00
I-180-500 In stock 500 g $ 349.00
I-180-1 In stock 1 kg $ 645.00
I-180-2.5 In stock 2.5 kg $ 1,525.00

Icariin

Catalog ID Size Pricing
I-215-1 1 g $ 175.00
I-215-5 5 g $ 479.00

Description

Icariin is a prenylflavonoid with anti-cancer properties and is studied for its diverse signaling effects observed in vivo. It has been documented to stimulate pathways that induce osteogenesis, decrease inflammation and promote angiogenesis.

Icariin has been shown in vivo to induce mice bone formation through upregulating runt-related transcription factor 2 (Runx2) genes and increasing bone morphogenic protein expression. These prompt osteogenic differentiation and bone development. Also, icariin invokes marrow stromal cell proliferation via increased alkaline phosphatase activity.

In vitro, icariin has been used to induce apoptosis by generating reactive oxygen species (ROS) and stimulating c-Jun N-terminal kinase (JNK) activity. Both of these apoptosis inducing processes compromise mitochondrial membranes to release cytochrome c. The generation of ROS causes direct damage to the membrane while JNK prompts downstream molecules to form pores in mitochondrial membranes.

Icariin has also been shown to inhibit nuclear factor-κB (NF-κB) expression, decreasing cytokine production. Additionally, icariin innervates phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) cell cycle pathways. The PI3K/AKT pathway has been demonstrated in vitro to induce angiogenesis, following the addition of icariin.

Product Specifications

Catalog ID I-215
CAS # 489-32-7
MW 676.66 g/mol
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I-215-1 2-3 Weeks 1 g $ 175.00
I-215-5 2-3 Weeks 5 g $ 479.00

Icaritin

Catalog ID Size Pricing
I-315-10 10 mg $ 198.00

Description

Icaritin is a prenylflavonoid derivative of icariin (Goldbio # I-215) and has been used for oncology research, to influence bone formation and displays neuroprotective effects. Applications in oncology and neurology research have been related to the activity of icaritin on estrogen receptors.

Within the field of cancer research, icaritin has been shown to act as an agonist and antagonist on estrogen receptors in vivo which was based upon concentration in different cancer lines. Icaritin was shown in vitro to sustain extracellular signal–regulated kinase (ERK) activity through stimulating estrogen receptors. Prolonged ERK activation arrested the cell cycle in the G2 stage and subsequently triggered apoptosis. Anti-cancer activity of icaritin has also been observed to occur in estrogen receptor negative cancer cells, showing an estrogen receptor independent pathway.

For Alzheimer’s research, icaritin has been investigated for attenuating cytotoxic effects caused by β-Amyloid proteins. While the mechanism for neuroprotection has not been elucidated, icaritin was shown to possibly exert these effects through mitogen-protein kinase (MAPK)/ERK cell signaling pathways.

Icaritin exerts an osteogenic effect in vivo by forming a bioactive scaffold that promotes bone growth while also increasing alkaline phosphatase (ALP) activity. It is also used to inhibit osteoclast differentiation and activity through suppression of receptor activator of nuclear factor kappa-B ligand (RANKL).

Product Specifications

Catalog ID I-315
CAS # 118525-40-9
MW 368.38 g/mol
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I-315-10 2-3 Weeks 10 mg $ 198.00

Icotinib hydrochloride

Catalog ID Size Pricing
I-560-10 10 mg $ 452.00

Description

Icotinib hydrochloride or icotinib HCl, is a first generation inhibitor of tyrosine kinase epidermal growth factor receptor (EGFR-TK). It has been used in measuring the efficacy of novel anti-cancer compounds in vivo against non-small-cell lung cancers that formed advanced solid tumors. Icotinib reversibly inhibits EGFR-TK competitively by blocking the ATP-binding site on tyrosine kinase.

Product Specifications

Catalog ID I-560
CAS # 1204313-51-8
MW 427.88 g/mol
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I-560-10 2-3 Weeks 10 mg $ 452.00

Idebenone

Catalog ID Size Pricing
I-850-5 5 g $ 107.00
I-850-10 10 g $ 169.00
I-850-25 25 g $ 302.00
I-850-50 50 g $ 462.00
I-850-100 100 g $ 888.00

Description

Idebenone is a synthetic analog of ubiquinone (CoQ10). It scavenges free radicals and acts as an antioxidant. Idebenone differs from ubiquinone by having a shorter, less lipophilic tail and thus can function in multiple cellular environments. In contrast to ubiquinone, idebenone acts as a competitive inhibitor of complex I in the electron transport chain and is capable of facilitating cellular respiration that is independent of a functioning complex I. It can accept electrons from the glycerophosphate shuttle, NADH-quinone oxidoreductase, and complex II of the electron transport chain. Idebenone was originally developed to treat cognitive disorders such as Alzheimer’s disease, but was not found to be effective so other uses are being explored.

Product Specifications

Storage/Handling Store at room temperature.
Catalog ID I-850
CAS # 58186-27-9
MW 338.44 g/mol
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Packs & Pricing
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I-850-5 2-3 Weeks 5 g $ 107.00
I-850-10 2-3 Weeks 10 g $ 169.00
I-850-25 2-3 Weeks 25 g $ 302.00
I-850-50 2-3 Weeks 50 g $ 462.00
I-850-100 2-3 Weeks 100 g $ 888.00

IFN-alpha1A, Human

Catalog ID Size Pricing
1160-01-100 100 μg $ 249.00
1160-01-500 500 μg $ 505.00

Description

Interferon alpha1 belongs to the type I interferon family and is encoded by the IFNA1 gene in humans. It is expressed in peripheral blood leukocytes and lymphoblastoid cells. It plays an important role in inducing non-specific resistance against a broad range of viral infections, and also affects cell proliferation and modulates immune responses. Interferon alpha proteins represent a group of related but distinct proteins that share over 95 % amino acid sequence homology. IFNA1 contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. IFNalpha1A differs from IFNalpha1B by having one alanine residue in a position where IFNalpha1B has a valine.

Product Specifications

Catalog ID 1160-01
MW ~19.5 kDa
Storage/Handling Store desiccated at -20°C.
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1160-01-100 3-4 Weeks 100 μg $ 249.00
1160-01-500 3-4 Weeks 500 μg $ 505.00

IFN-alpha1B, Human

Catalog ID Size Pricing
1160-02-10 10 μg $ 165.00

Description

Interferon alpha1 belongs to the type I interferon family and is encoded by the IFNA1 gene in humans. It is expressed in peripheral blood leukocytes and lymphoblastoid cells. It plays an important role in inducing non-specific resistance against a broad range of viral infections. It also affects cell proliferation and modulates immune responses. Interferon alpha proteins represent a group of related but distinct proteins that share over 95 % amino acid sequence homology. IFNA1 contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. IFNalpha1B differs from IFNalpha1A by having one valine residue in a position where IFNalpha1A has an alanine.

Product Specifications

Catalog ID 1160-02
MW ~19.5 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1160-02-10 3-4 Weeks 10 μg $ 165.00

IFN-alpha2A, Human

Catalog ID Size Pricing
1160-03-100 100 μg $ 249.00
1160-03-500 500 μg $ 505.00

Description

Interferon alpha2 belongs to the type I interferon family and is encoded by the IFNA2 gene in humans. Like the other IFN-alpha proteins, it is expressed in leukocytes and plays an important role in inducing non-specific resistance against a broad range of viral infections. Recombinant IFN-alpha2A has been used to induce regression of corticosteroid-resistant hemangiomas in infancy. IFNA2 is one of 13 subtypes of interferon alpha found in humans, clustered on chromosome 9. It contains four highly conserved cysteine residues forming two disulfide bonds, one of which is necessary for biological activity.

Product Specifications

Catalog ID 1160-03
MW ~19.2 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1160-03-100 3-4 Weeks 100 μg $ 249.00
1160-03-500 In stock 500 μg $ 505.00

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