CCL3, Rat

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Product Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Chemokine (C-C motif) Ligand 3 (CCL3)
Monocyte Chemoattractant Protein 1, Alpha (MCP1α, MCP-1α)
Small Inducible Cytokine Subfamily A Member 3 (SCYA3)
Macrophage Inflammatory Protein 1, Alpha (MIP1A)
G0/G1 Switch Gene 19-1 (GOS-19-1)

Rat CCL3 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed by T-cells, B-cells, macrophages, and various tumor cells lines and has been identified as a G0/G1 switch gene in various cells. CCL3 is the primary stimulator of TNF secretion and is chemotactic for polymorphonuclear leukocytes. CCL3 induces superoxide production by neutrophils, plays an inhibitory role in hematopoiesis, and displays inhibitory activity against strains of HIV-1, HIV-2, and SIV. CCL3 is a ligand for CCR1, CCR4, and the HIV-1 coreceptor CCR5. Activation of CCR5 through CCL3 activates a G-protein pathway through GNAI2 and a tyrosine phosphorylation through JAK2.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~7.9 kDa (69 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 10-100 ng/ml.

Storage/Handling: Store desiccated at -20°C.

RGD: 3647


Additional resources for this protein may be found at:

Product Specifications

Catalog ID 2540-03
MW ~7.9 kDa
Storage/Handling Store desiccated at -20°C.

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$12.99 Ground shipping (In continental US only.)

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