R_Products

Streptavidin Agarose Resin is a high affinity biotin-binding chromatography resin with streptavidin covalently bound to 6% crosslinked agarose beads and a biotin binding capacity of >120 nmol/ml of gel. Immobilized Streptavidin resin is suitable for gravity flow columns, spin columns, and FPLC methods. Immobilized Streptavidin can be used for affinity chromatography purifications by separating biotinylated proteins from nonbiotinylated proteins and for affinity purification of antigens when used with biotinylated antibodies.

Vascular endothelial growth factor is a potent growth factor and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Two receptor tyrosine kinases (RTKs), Flt-1 and Flk-1 have been shown to bind VEGF with high affinity.