• object(anvilstl\commercio\models\Category)#394 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(184) ["root"]=> int(1) ["lft"]=> int(260) ["rgt"]=> int(261) ["level"]=> int(3) ["name"]=> string(10) "Chemokines" ["url_name"]=> string(10) "chemokines" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(710) "Chemokines are a family of small, inducible secreted cytokine proteins that are known for their conserved structural homology as well as their ability to mediate chemotaxis of various cells. They are essential for development and regulation of the immune system during both homeostasis and infection. Chemokines are usually divided into four subgroups based on the placement of conserved cysteine residues that are essential for tertiary structure. CC, CXC, CX3C, and XC chemokines refer to the number of amino acids separating the first two cysteine residues. GoldBio offers close to 100 different recombinant chemokines, which includes a variety of homeostatic and inflammatory chemokines from each subgroup." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(158) "Chemokines are a family of cytokines that mediate chemotaxis and are important for immune system regulation. GoldBio offers close to 100 different chemokines." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(184) ["root"]=> int(1) ["lft"]=> int(260) ["rgt"]=> int(261) ["level"]=> int(3) ["name"]=> string(10) "Chemokines" ["url_name"]=> string(10) "chemokines" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(710) "Chemokines are a family of small, inducible secreted cytokine proteins that are known for their conserved structural homology as well as their ability to mediate chemotaxis of various cells. They are essential for development and regulation of the immune system during both homeostasis and infection. Chemokines are usually divided into four subgroups based on the placement of conserved cysteine residues that are essential for tertiary structure. CC, CXC, CX3C, and XC chemokines refer to the number of amino acids separating the first two cysteine residues. GoldBio offers close to 100 different recombinant chemokines, which includes a variety of homeostatic and inflammatory chemokines from each subgroup." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(158) "Chemokines are a family of cytokines that mediate chemotaxis and are important for immune system regulation. GoldBio offers close to 100 different chemokines." 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} [1]=> string(11) "afterInsert" } [1]=> NULL } } ["beforeUpdate"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#397 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } [1]=> string(12) "beforeUpdate" } [1]=> NULL } } ["afterUpdate"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#397 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" 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object(creocoder\nestedsets\NestedSetsBehavior)#422 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } [1]=> string(12) "beforeInsert" } [1]=> NULL } } ["afterInsert"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#422 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL 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  • object(anvilstl\commercio\models\Category)#423 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(232) ["root"]=> int(1) ["lft"]=> int(33) ["rgt"]=> int(34) ["level"]=> int(2) ["name"]=> string(10) "R_Products" ["url_name"]=> string(10) "r-products" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(0) "" ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(0) "" ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(232) ["root"]=> int(1) ["lft"]=> int(33) 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  • CCL22, Rat

    {{ i.item.name }}

    Product Description

    GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

    Recombinant Rat Chemokine (C-C motif) Ligand 22 (CCL22)
    Stimulated T Cell Chemotactic Protein 1 (STCP-1)
    Small Inducible Cytokine Subfamily A Member 22 (SCYA22)
    Macrophage-Derived Chemokine (MDC)

    Rat CCL22 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in activated splenic B-cells, macrophages, and dendritic cells. Expression of CCL22 is induced by IL4, IL13, and IFNG and inhibited by IL10. Increased expression CCL22 has also been observed after incubation of mast cells with TNF-alpha or IgE. CCL22 is chemotactic for chronically activated T-cells and plays a role in trafficking activated T cells. It also plays a role in migration and survival of cells expressing FOXP3. CCL22 is a ligand for CCR4.

    Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

    Source: Escherichia coli

    MW: ~7.9 kDa (68 amino acids)

    Purity: >96% by SDS-PAGE and HPLC analyses

    Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.

    Storage/Handling: Store desiccated at -20°C.

    RGD: 619933

    NOT FOR HUMAN USE!

    Additional resources for this protein may be found at:
    OMIM

    Product Specifications

    Catalog ID 2540-22
    MW ~7.9 kDa
    Storage/Handling Store desiccated at -20°C.

    View Sizes & Pricing

    Catalog Number:
    {{ currentSelection && currentSelection.sku ? currentSelection.sku : '...' }}
    CAS Number:
    {{ casNumber && casNumber.value ? casNumber.value : '...' }}
    Size:
    Quantity:
    On Sale:
    ${{ currentSelection.price }} ${{ currentSelection.sale_price }}
    Shipping:
    $9.99 Ground shipping (In continental US only.)

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