• object(anvilstl\commercio\models\Category)#413 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(184) ["root"]=> int(1) ["lft"]=> int(260) ["rgt"]=> int(261) ["level"]=> int(3) ["name"]=> string(10) "Chemokines" ["url_name"]=> string(10) "chemokines" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(710) "Chemokines are a family of small, inducible secreted cytokine proteins that are known for their conserved structural homology as well as their ability to mediate chemotaxis of various cells. They are essential for development and regulation of the immune system during both homeostasis and infection. Chemokines are usually divided into four subgroups based on the placement of conserved cysteine residues that are essential for tertiary structure. CC, CXC, CX3C, and XC chemokines refer to the number of amino acids separating the first two cysteine residues. GoldBio offers close to 100 different recombinant chemokines, which includes a variety of homeostatic and inflammatory chemokines from each subgroup." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(158) "Chemokines are a family of cytokines that mediate chemotaxis and are important for immune system regulation. GoldBio offers close to 100 different chemokines." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(184) ["root"]=> int(1) ["lft"]=> int(260) ["rgt"]=> int(261) ["level"]=> int(3) ["name"]=> string(10) "Chemokines" ["url_name"]=> string(10) "chemokines" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(710) "Chemokines are a family of small, inducible secreted cytokine proteins that are known for their conserved structural homology as well as their ability to mediate chemotaxis of various cells. They are essential for development and regulation of the immune system during both homeostasis and infection. Chemokines are usually divided into four subgroups based on the placement of conserved cysteine residues that are essential for tertiary structure. CC, CXC, CX3C, and XC chemokines refer to the number of amino acids separating the first two cysteine residues. GoldBio offers close to 100 different recombinant chemokines, which includes a variety of homeostatic and inflammatory chemokines from each subgroup." ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(158) "Chemokines are a family of cytokines that mediate chemotaxis and are important for immune system regulation. GoldBio offers close to 100 different chemokines." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_related":"yii\db\BaseActiveRecord":private]=> array(0) { } ["_relationsDependencies":"yii\db\BaseActiveRecord":private]=> array(0) { } ["_errors":"yii\base\Model":private]=> NULL ["_validators":"yii\base\Model":private]=> NULL ["_scenario":"yii\base\Model":private]=> string(7) "default" ["_events":"yii\base\Component":private]=> array(6) { ["beforeInsert"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#416 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { 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} [1]=> string(11) "afterInsert" } [1]=> NULL } } ["beforeUpdate"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#416 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } [1]=> string(12) "beforeUpdate" } [1]=> NULL } } ["afterUpdate"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#416 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" 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NULL } } } ["_eventWildcards":"yii\base\Component":private]=> array(0) { } ["_behaviors":"yii\base\Component":private]=> array(1) { ["tree"]=> object(creocoder\nestedsets\NestedSetsBehavior)#416 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } } ["__fieldGroups":protected]=> array(0) { } }
  • object(anvilstl\commercio\models\Category)#440 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(219) ["root"]=> int(1) ["lft"]=> int(7) ["rgt"]=> int(8) ["level"]=> int(2) ["name"]=> string(10) "C_Products" ["url_name"]=> string(10) "c-products" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(0) "" ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(0) "" ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(219) ["root"]=> int(1) ["lft"]=> int(7) ["rgt"]=> 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object(creocoder\nestedsets\NestedSetsBehavior)#441 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } [1]=> string(12) "beforeInsert" } [1]=> NULL } } ["afterInsert"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#441 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL 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  • object(anvilstl\commercio\models\Category)#442 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(232) ["root"]=> int(1) ["lft"]=> int(33) ["rgt"]=> int(34) ["level"]=> int(2) ["name"]=> string(10) "R_Products" ["url_name"]=> string(10) "r-products" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(0) "" ["hide"]=> int(0) ["third_party_id"]=> NULL ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(0) "" ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(232) ["root"]=> int(1) ["lft"]=> int(33) 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object(creocoder\nestedsets\NestedSetsBehavior)#443 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL ["owner"]=> *RECURSION* ["_attachedEvents":"yii\base\Behavior":private]=> array(6) { ["beforeInsert"]=> string(12) "beforeInsert" ["afterInsert"]=> string(11) "afterInsert" ["beforeUpdate"]=> string(12) "beforeUpdate" ["afterUpdate"]=> string(11) "afterUpdate" ["beforeDelete"]=> string(12) "beforeDelete" ["afterDelete"]=> string(11) "afterDelete" } } [1]=> string(12) "beforeInsert" } [1]=> NULL } } ["afterInsert"]=> array(1) { [0]=> array(2) { [0]=> array(2) { [0]=> object(creocoder\nestedsets\NestedSetsBehavior)#443 (8) { ["treeAttribute"]=> string(4) "root" ["leftAttribute"]=> string(3) "lft" ["rightAttribute"]=> string(3) "rgt" ["depthAttribute"]=> string(5) "level" ["operation":protected]=> NULL ["node":protected]=> NULL 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  • CCL3, Rat

    {{ i.item.name }}

    Product Description

    GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

    Recombinant Rat Chemokine (C-C motif) Ligand 3 (CCL3)
    Monocyte Chemoattractant Protein 1, Alpha (MCP1α, MCP-1α)
    Small Inducible Cytokine Subfamily A Member 3 (SCYA3)
    LD78-Alpha
    Macrophage Inflammatory Protein 1, Alpha (MIP1A)
    G0/G1 Switch Gene 19-1 (GOS-19-1)

    Rat CCL3 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed by T-cells, B-cells, macrophages, and various tumor cells lines and has been identified as a G0/G1 switch gene in various cells. CCL3 is the primary stimulator of TNF secretion and is chemotactic for polymorphonuclear leukocytes. CCL3 induces superoxide production by neutrophils, plays an inhibitory role in hematopoiesis, and displays inhibitory activity against strains of HIV-1, HIV-2, and SIV. CCL3 is a ligand for CCR1, CCR4, and the HIV-1 coreceptor CCR5. Activation of CCR5 through CCL3 activates a G-protein pathway through GNAI2 and a tyrosine phosphorylation through JAK2.

    Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

    Source: Escherichia coli

    MW: ~7.9 kDa (69 amino acids)

    Purity: >98% by SDS-PAGE and HPLC analyses

    Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 10-100 ng/ml.

    Storage/Handling: Store desiccated at -20°C.

    RGD: 3647

    NOT FOR HUMAN USE!

    Additional resources for this protein may be found at:
    OMIM

    Product Specifications

    Catalog ID 2540-03
    MW ~7.9 kDa
    Storage/Handling Store desiccated at -20°C.

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    On Sale:
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    Shipping:
    $9.99 Ground shipping (In continental US only.)

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