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Nickel NTA Agarose Beads

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Catalog ID Size Pricing
H-350-5 5 mL $ 75.00
H-350-10 10 mL $ 119.00
H-350-25 25 mL $ 255.00
H-350-50 50 mL $ 439.00
H-350-100 100 mL $ 825.00
H-350-500 500 mL $ 3,625.00

Description

Nickel-NTA Agarose Resin has a binding capacity of ~50 mg/ml. In addition, it allows for purification of proteins under native or denaturing conditions. GoldBio Nickel Agarose works very well with the His-Tag Buffer Set.

NTA cross-linked Agarose resin consists of nitrilotriacetic acid groups ligated by stable ether linkages via a spacer arm. NTA is a tetravalent chelating agent, covalently coupled to cross-linked agarose beads, providing a higher specificity and lower ion leaching than IDA linked resins. NTA resins have also been shown to be more robust in the presence of higher concentrations of EDTA, but may require a higher imidazole concentration for protein elution. This resin is loaded with Ni 2+. The resulting, ready-to-use resin is ideal for rapid purifications of His-tagged proteins.

Product Specifications

Catalog ID H-350
Storage/Handling store at 4°C. Do NOT freeze.
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Packs & Pricing
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H-350-5 In stock 5 mL $ 75.00
H-350-10 In stock 10 mL $ 119.00
H-350-25 In stock 25 mL $ 255.00
H-350-50 In stock 50 mL $ 439.00
H-350-100 In stock 100 mL $ 825.00
H-350-500 In stock 500 mL $ 3,625.00

Nickel NTA HTC Agarose Beads

There is no image for Nickel NTA HTC Agarose Beads Nickel NTA HTC Agarose Beads
Catalog ID Size Pricing
H-355-25 25 mL $ 325.00
H-355-100 100 mL $ 1,084.00
H-355-500 500 mL $ 4,661.00

Description

Nickel NTA HTC Agarose Resin has a binding capacity of ~60 mg/ml. In addition, it allows for purification of proteins under native or denaturing conditions. GoldBio Nickel Agarose works very well with the His-Tag Buffer Set.

NTA cross-linked Agarose resin consists of nitrilotriacetic acid groups ligated by stable ether linkages via a spacer arm. NTA is a tetravalent chelating agent, covalently coupled to cross-linked agarose beads, providing a higher specificity and lower ion leaching than IDA linked resins. NTA resins have also been shown to be more robust in the presence of higher concentrations of EDTA, but may require a higher imidazole concentration for protein elution. This resin is loaded with Ni 2+. The resulting, ready-to-use resin is ideal for rapid purifications of His-tagged proteins.

Product Specifications

Catalog ID H-355
Storage/Handling store at 4°C. Do NOT freeze.
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Packs & Pricing
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H-355-25 2-3 Weeks 25 mL $ 325.00
H-355-100 2-3 Weeks 100 mL $ 1,084.00
H-355-500 2-3 Weeks 500 mL $ 4,661.00

Nickel NTA Magnetic Agarose Beads

Catalog ID Size Pricing
H-351-2 2 mL $ 114.00
H-351-5 5 mL $ 255.00
H-351-10 10 mL $ 460.00

Description

Nickel NTA Magnetic Agarose Beads are a rapid and easy small scale purification of histidine-tagged proteins. This resin consists of magnetic agarose derivatized with Nitrilotriacetic (NTA) and provides good properties working in native or denaturing conditions. Magnetic agarose beads provide a convenient and quick method for purification without the need for pipetting or centrifugation. Washing, binding and elution steps will require a magnetic device.

NTA cross-linked resins consist of nitrilotriacetic acid groups ligated by stable ether linkages via a spacer arm. NTA is a tetravalent chelating agent which provides a higher specificity and lower ion leaching than IDA linked resins. NTA resins have also been shown to be more robust in the presence of higher concentrations of EDTA, but may require a higher imidazole concentration for protein elution. This resin is loaded with Ni 2+. The resulting, ready-to-use resin is ideal for rapid purifications of His-tagged proteins.

Product Specifications

Catalog ID H-351
Storage/Handling store at 4°C. Do NOT freeze.
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Packs & Pricing
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H-351-2 In stock 2 mL $ 114.00
H-351-5 2-3 Weeks 5 mL $ 255.00
H-351-10 In stock 10 mL $ 460.00

Nicotinamide (Vitamin B3), USP Grade

Catalog ID Size Pricing
N-640-500 500 g $ 132.00

Description

Nicotinamide is a metabolized amide form of vitamin B3. It is an anti-cancer agent and inhibitor of PARP-1, which is responsible for repairing DNA damage caused by chemotherapy. Nicotinamide is converted to nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) for use in biological redox reactions. Additionally, nicotinamide is a nicotinamide phosphoribosyltransferase (NAMPT) substrate and anti-inflammatory agent.

Product Specifications

Catalog ID N-640
CAS # 98-92-0
MW 122.12 g/mol
Storage/Handling Store at 4°C.
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N-640-500 2-3 Weeks 500 g $ 132.00

Nigericin Sodium Salt

Catalog ID Size Pricing
N-650-10 10 mg $ 216.00
N-650-50 50 mg $ 760.00

Description

Nigericin is an ionophore antibiotic isolated from Streptomyces hygroscopicus. It has been shown to suppress DNA synthesis in Ehrlich ascites carcinoma. Nigericin is insoluble in water, but soluble in methanol and chloroform.

Nigericin sodium disrupts membrane potential by acting as an antiporter of H+ and K+ ions by exchanging K+ for H+. This causes a rapid decrease in intracellular pH.

Product Specifications

Catalog ID N-650
CAS # 28380-24-7
MW 746.94 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-650-10 2-3 Weeks 10 mg $ 216.00
N-650-50 2-3 Weeks 50 mg $ 760.00

Nisin

Catalog ID Size Pricing
N-660-1 1 g $ 64.00
N-660-5 5 g $ 169.00
N-660-25 25 g $ 588.00

Description

Nisin is a polypeptide antibiotic known as a lantibiotic. It has been isolated from Lactococcus lactis. Produced by gram-positive bacteria, the role of nisin is to reduce competitive strain due to the presence of other gram-positive bacteria.

Product Specifications

Catalog ID N-660
CAS # 1414-45-5
MW 3354.07 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-660-1 2-3 Weeks 1 g $ 64.00
N-660-5 2-3 Weeks 5 g $ 169.00
N-660-25 2-3 Weeks 25 g $ 588.00

Nitrofurantoin, USP Grade

Catalog ID Size Pricing
N-690-100 100 g $ 190.00
N-690-250 250 g $ 261.00

Description

Nitrofurantoin is a bacteriostatic, nitrofuran antibiotic targeting gram-negative and gram-positive bacteria such as Enterococci, Staphylococci, Streptococci, Corynebacterium, and E. Coli. It has been used to study nitrofurantoin bacterial susceptibility and nitrofurantoin-induced toxicity. Additionally, it is a substrate for bacterial nitrofuran reductase.

Product Specifications

Catalog ID N-690
CAS # 67-20-9
MW 238.16 g/mol
Storage/Handling Store at 4°C. Protect from light.
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N-690-100 2-3 Weeks 100 g $ 190.00
N-690-250 2-3 Weeks 250 g $ 261.00

Nitrotetrazolium blue chloride (NBT)

Catalog ID Size Pricing
NBT1 1 g $ 69.00
NBT2.5 2.5 g $ 125.00
NBT5 5 g $ 205.00
NBT10 10 g $ 325.00

Description

Nitrotetrazolium Blue (NBT) is used in combination with 5-bromo-4-chloro-3-indoxyl phosphate (BCIP) to detect alkaline phosphatase activity in blotting techniques and in situ hybridization chemistry. BCIP acts as the substrate for alkaline phosphatase, and the oxidizing reagent NBT enhances the purple-brown final color of the precipitates at the reaction sites.

NBT has also been used with X-Gal,or Salmon-Gal to speed up and enhance colony screening.

Product Specifications

Catalog ID NBT
CAS # 298-83-9
MW 817.65 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C. Protect from light.
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NBT1 In stock 1 g $ 69.00
NBT2.5 In stock 2.5 g $ 125.00
NBT5 In stock 5 g $ 205.00
NBT10 In stock 10 g $ 325.00

Noggin, Human

Catalog ID Size Pricing
1180-09-5 5 μg $ 115.00
1180-09-100 100 μg $ 905.00
1180-09-500 500 μg $ 1,849.00

Description

Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-β (Transforming Growth Factor) family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Noggin has been shown to modulate the activities of other BMPs including BMP2, 7, 13, and 14. Targeted deletion of noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Transgenic mice over-expressing noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation and severe osteoporosis.

Product Specifications

Catalog ID 1180-09
MW ~46.2 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1180-09-5 In stock 5 μg $ 115.00
1180-09-100 3-4 Weeks 100 μg $ 905.00
1180-09-500 3-4 Weeks 500 μg $ 1,849.00

Noggin, Murine

Catalog ID Size Pricing
1380-09-5 5 μg $ 115.00
1380-09-100 100 μg $ 905.00
1380-09-500 500 μg $ 1,849.00

Description

Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-β (Transforming Growth Factor) family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Noggin has been shown to modulate the activities of other BMPs including BMP2, 7, 13 and 14. Targeted deletion of noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Transgenic mice overexpressing noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis.

Product Specifications

Catalog ID 1380-09
MW ~46.4 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1380-09-5 3-4 Weeks 5 μg $ 115.00
1380-09-100 In stock 100 μg $ 905.00
1380-09-500 3-4 Weeks 500 μg $ 1,849.00

Norfloxacin

Catalog ID Size Pricing
N-700-5 5 g $ 84.00
N-700-10 10 g $ 148.00

Description

Norfloxacin is a first generation fluoroquinolone antibiotic targeting primarily gram-negative bacteria responsible for causing urinary tract infections. It is a derivative of pefloxacin.

Product Specifications

Catalog ID N-700
CAS # 70458-96-7
MW 319.33 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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N-700-5 2-3 Weeks 5 g $ 84.00
N-700-10 2-3 Weeks 10 g $ 148.00

Nourseothricin Sulfate (Streptothricin Sulfate) (NTC or clonNAT)

Catalog ID Size Pricing
N-500-100 100 mg $ 85.00
N-500-500 500 mg $ 225.00
N-500-1 1 g $ 329.00
N-500-2 2 x 1 g $ 599.00
N-500-3 3 x 1 g $ 855.00
N-500-4 4 x 1 g $ 1,089.00
N-500-5 5 x 1 g $ 1,299.00

Description

Nourseothricin is a broad-spectrum antibiotic derived from Streptomyces noursei. In addition to being effective on prokaryotic cells of gram-positive and gram-negative bacteria, various fungi including Candida albicans, and certain DNA and RNA viruses, it is also effective on eukaryotic cells of higher eukaryotes. It has been used as a selection agent for cells containing the gene conferring resistance to it.

GoldBio nourseothricin is a mixture of four streptothricin compounds: D and F (>85%) as well as C and E (<15%).

Product Specifications

Catalog ID N-500
CAS # 96736-11-7
MW Streptothricin D (758.86 g/mol), Streptothricin F (502.52 g/mol), Streptothricin E (630.69 g/mol), Streptothricin C (887.04 g/mol)
Storage/Handling Store desiccated at 4°C.
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Packs & Pricing
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N-500-100 In stock 100 mg $ 85.00
N-500-500 In stock 500 mg $ 225.00
N-500-1 In stock 1 g $ 329.00
N-500-2 In stock 2 x 1 g $ 599.00
N-500-3 In stock 3 x 1 g $ 855.00
N-500-4 In stock 4 x 1 g $ 1,089.00
N-500-5 In stock 5 x 1 g $ 1,299.00

NOV, Human

Catalog ID Size Pricing
1150-01B9-5 5 μg $ 115.00

Description

NOV is a dynamically expressed, multifunctional matricellular protein of the CCN (CTGF/CYR61/NOV) family encoded by the NOV gene. It is expressed in certain tumors, including Wilm’s tumor and most nephroblastomas. Expression of NOV has been reported to reduce tumorgenicity and reduce proliferation of certain cancer cell lines. It has also been shown to induce angiogenesis in endothelial cells and stimulate cell migration in many mesenchymal cell types. Recombinant human NOV is a 36.2 kDa protein containing 331 amino acid residues and it shares 80% and 81% amino acid identity with rat and murine NOV.

Product Specifications

Catalog ID 1150-01B9
MW ~36.2 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1150-01B9-5 3-4 Weeks 5 μg $ 115.00

NOV, Murine

Catalog ID Size Pricing
1350-01B9-5 5 μg $ 115.00

Description

NOV is a dynamically expressed, multifunctional matricellular protein of the CCN (CTGF/CYR61/NOV) family encoded by the NOV gene. It is expressed in certain tumors, including Wilm’s tumor and most nephroblastomas. Expression of NOV has been reported to reduce tumorgenicity and reduce proliferation of certain cancer cell lines. It has also been shown to induce angiogenesis in endothelial cells and stimulate cell migration in many mesenchymal cell types. Recombinant murine NOV is a 36.4 kDa protein containing 333 amino acid residues and it shares 92% and 82% amino acid identity with rat and human NOV.

Product Specifications

Catalog ID 1350-01B9
MW ~36.4 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1350-01B9-5 3-4 Weeks 5 μg $ 115.00

Novobiocin Sodium Salt

Catalog ID Size Pricing
N-451-10 10 g $ 500.00

Description

Novobiocin Sodium Salt is an aminocoumarin antibiotic targeting gram-positive bacteria. It is used as a tool to produce positively-supercoiled plasmid DNA and in heat shock protein studies as it is an inhibitor of Hsp90.

Novobiocin functions as an competitive inhibitor of prokaryotic DNA gyrase and eukaryotic DNA topoisomerase II. By inhibition of these enzymes, novobiocin blocks DNA synthesis, ultimately causing cell death.

Product Specifications

Catalog ID N-451
CAS # 1476-53-5
MW 634.60 g/mol
Storage/Handling Store desiccated at -20°C.
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N-451-10 2-3 Weeks 10 g $ 500.00

NPPB, Human

Catalog ID Size Pricing
1170-09-100 100 μg $ 365.00

Description

Natriuretic Peptide B is synthesized as a 134 residue preprohormone before a signal peptide is cleaved, creating a storage protein which is further cleaved into the 32 residue, biologically active peptide that is secreted into the blood. NPPB was first discovered in porcine brain, but is produced mainly by cardiac ventricle cells in humans. It acts as a cardiac hormone with a variety of functions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Additionally, it plays a key role in cardiovascular homeostasis, helps restore the body's salt and water balance, and improves heart function. NPPB also has antimicrobial properties against Gram-positive and Gram-negative bacteria as well as yeast in a dose-dependent manner.

Product Specifications

Catalog ID 1170-09
MW ~3.5 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1170-09-100 3-4 Weeks 100 μg $ 365.00

NRG1-alpha, Human

Catalog ID Size Pricing
1170-20-10 10 μg $ 115.00

Description

Neuregulin 1 belongs to a family of structurally related polypeptide growth factors and is produced in numerous isoforms by alternative splicing, which allows it to perform a wide variety of functions. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They all have the EGF-like domain, and can bind to ErbB3 and ErbB4 receptor tyrosine kinases. This binding induces ErbB3 and ErbB4 heterodimerization with ErbB2, stimulating intrinsic kinase activity. This product is the EGF-like domain of isoform 1. NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells. Isoform 1 induces differentiation of mammary tumor cells, including altered morphology and synthesis of milk components. NRG1 is necessary for cardiac development, structural maintenance, and functional integrity of the heart. It is also thought to play a role in synaptic plasticity. Dysregulation of NRG1 has been linked to various cancers and schizophrenia.

Product Specifications

Catalog ID 1170-20
MW ~7.4 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1170-20-10 3-4 Weeks 10 μg $ 115.00

NRG1-beta1 (177-241 a.a.), Human

Catalog ID Size Pricing
1170-10B-10 10 μg $ 115.00

Description

Neuregulin 1 belongs to a family of structurally related polypeptide growth factors and is produced in numerous isoforms by alternative splicing, which allows it to perform a wide variety of functions. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They all have the EGF-like domain, and can bind to ErbB3 and ErbB4 receptor tyrosine kinases. This binding induces ErbB3 and ErbB4 heterodimerization with ErbB2, stimulating intrinsic kinase activity. This recombinant protein is the EGF-like domain (177-241 a.a.) of isoform 6, the major neuronal isoform. NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells. NRG1 is necessary for development, structural maintenance, and functional integrity of the heart. It is also thought to play a role in synaptic plasticity. Dysregulation of NRG1 has been linked to various cancers and schizophrenia.

Product Specifications

Catalog ID 1170-10B
MW ~7.5 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1170-10B-10 3-4 Weeks 10 μg $ 115.00

NRG1-beta2, Human

Catalog ID Size Pricing
1170-10-10 10 μg $ 115.00
1170-10-100 100 μg $ 355.00
1170-10-500 500 μg $ 749.00

Description

Neuregulin 1 belongs to a family of structurally related polypeptide growth factors and is produced in numerous isoforms by alternative splicing, which allows it to perform a wide variety of functions. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They all have the EGF-like domain, and can bind to ErbB3 and ErbB4 receptor tyrosine kinases. This binding induces ErbB3 and ErbB4 heterodimerization with ErbB2, stimulating intrinsic kinase activity. This recombinant protein is the EGF-like domain of isoform 7. NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells. NRG1 is necessary for development, structural maintenance, and functional integrity of the heart. It is also thought to play a role in synaptic plasticity. Dysregulation of NRG1 has been linked to various cancers and schizophrenia.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Product Specifications

Catalog ID 1170-10
MW ~7.0 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
,
1170-10-10 3-4 Weeks 10 μg $ 115.00
1170-10-100 3-4 Weeks 100 μg $ 355.00
1170-10-500 3-4 Weeks 500 μg $ 749.00

NRN1, Human

There is no image for NRN1, Human NRN1, Human
Catalog ID Size Pricing
1170-22-5 5 μg $ 115.00

Description

Neuritin (NRN1) is a GPI-anchored neurotrophic factor, which is expressed in response to induction of neuronal activity by GDNF, BDNF, NT3 and other neural stimulators. It promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. NRN1 also promotes angiogenesis. During early brain development, NRN1 inhibits apoptosis of cortical progenitors by preventing activation of caspase 3. Recombinant human neuritin is a covalently disulfide-linked homodimer, consisting of two 9.7 kDa polypeptide monomers, each containing 88 amino acid residues.

Product Specifications

Catalog ID 1170-22
MW ~19.4 kDa
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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1170-22-5 3-4 Weeks 5 μg $ 115.00

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