{{ i.item.name }}
Specifications Documentation Citations Related Products
1
Request Lot Specific COA Citation Search Tool
Leave Product Feedback

Product Description

TCEP (Tris (2-Carboxyethyl) phosphine Hydrochloride) is an odorless reducing agent suitable for protein applications and in the preparation for electrophoresis. TCEP is water soluble, is stable in a variety of solutions and is particularly useful in the labeling of cysteine residues with maleimides, preventing the cysteines from forming disulfide bonds. As a reducing agent, TCEP has many other desirable features, including:

• TCEP-HCl is stable in air.
• TCEP-HCl is odorless so reactions can be carried out on the bench without the need for a fume hood.
• TCEP-HCl is efficient and can be used to reduce disulfide bonds at low concentrations.
• TCEP-HCl is selective for disulfides and does not react with other protein side chains.
• TCEP-HCl may be used as a substitute for DTT at a final concentration of 50mM.

Product Specifications
TCEP-HCl;
Tris (2-Carboxyethyl) phosphine Hydrochloride

Molecular Biology Grade
Protease Free

Formula: C9H15O6P • HCl

MW: 286.65 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 2734570

  • TCEP 50 g and 100 g ships as multiple 25 g units to qualify for a small quantity exception to hazardous fees.

  • Due to hazardous goods restrictions, this product cannot ship by ground shipping to Canada or Mexico.

Product Specifications

Catalog ID TCEP
CAS # 51805-45-9
MW 286.65 g/mol
Storage/Handling Store desiccated at -20°C.

Related Products

4-Nitrophenyl-β-D- xylopyranoside
View
Packs & Pricing
,
N-410-500 500 mg $ 75.00
N-410-2.5 2.5 g $ 219.00
N-410-5 5 g $ 359.00
N-410-10 10 g $ 595.00
DTT (Dithiothreitol) (> 99% pure) Protease free
View
Packs & Pricing
,
DTT10 10 g $ 59.00
$ 55.00
DTT25 25 g $ 129.00
$ 119.00
DTT50 50 g $ 229.00
$ 216.00
DTT100 100 g $ 369.00
$ 347.00
DTT500 500 g $ 1,645.00
$ 1,549.00
Nickel Agarose Beads (High Density)
View
Packs & Pricing
,
H-320-5 5 mL $ 59.00
H-320-10 10 mL $ 99.00
H-320-25 25 mL $ 219.00
H-320-50 50 mL $ 365.00
H-320-100 100 mL $ 649.00
H-320-500 500 mL $ 2,649.00

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet
P
TCEP Stock Solution

TCEP Stock Solution - 0.5M
P
Protein Digestion utilizing Trypsin

Digestion of Proteins utilizing Trypsin Protocol
C
Sample COA - TCEP

Sample Certificate of Analysis - TCEP
COA for example only. Actual tests may differ.
S
SDS (MSDS) - TCEP

Safety Data Sheet

Citations

Featured Articles

Reducing Agents (Part 4 of 4) - TCEP-HCl (Tris-(carboxyethyl) phosphine hydrochloride)
Previously, we’ve been discussing the function of various reducing agents. There are a number of red...
This vs. That – Your Guide to Choosing Between Similar Reagents
There are a lot of products in the lab that do similar things but were developed for a specialized...
All about TCEP—the Odorless Reducing Agent
Article Contents What is TCEP? Sulfhydril Groups and Disulfide Bridges in Proteins TCEP and Reduc...

View Sizes & Pricing

Catalog Number:
{{ currentSelection && currentSelection.sku ? currentSelection.sku : '...' }}
CAS Number:
{{ casNumber && casNumber.value ? casNumber.value : '...' }}
Size:
Quantity:
On Sale:
${{ currentSelection.price }} ${{ currentSelection.sale_price }}
Availability:
{{ currentSelection.availability }}
Shipping:
$12.99 Ground shipping (In continental US only.)

Join our list to receive promos and articles.

Join Now
GoldBio ©2023 All Rights Reserved Privacy Policy
Gold Biotechnology (U.S. Registration No 3,257,927) and Goldbio (U.S. Registration No 3,257,926) are registered trademarks of Gold Biotechnology, Inc.
NSF Logo
Sign In
1.800.248.7609
Back