Hygromycin B

Product Description

Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It is commonly used to study protein synthesis. Aside from its efficacy against bacteria, fungi, and higher eukaryotic cells, hygromycin B is also an antiviral agent inhibiting translation upon selectively entering cells made permeable due to viral infection. It works as a standard selection antibiotic in gene experiments, especially for selection of hygromycin resistance gene transformed cells.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.


Product Specifications
Hygromycin B

Formula: C20H37N3O13

MW: 527.52 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 35766

International shipments MUST be shipped by air (including Canada and Mexico). Shipments of 25 g, 50 g and 100 g will be shipped as multiples of 25 g units to qualify for the small quantity exception. 500 g pack sizes are a hazardous shipment and will incur a hazmat fee, which we estimate to be $65.

Product Specifications

Catalog ID H-270
CAS # 31282-04-9
MW 527.52 g/mol
Storage/Handling Store desiccated at -20°C.
UN Number 3462
Item Class 6.1
Group Number I

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$12.99 Ground shipping (In continental US only.)

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