Enhancing the Inhibition of Cancer Cells
Autophagy is a very complicated process when it comes to cancer. In general, autophagy isn’t compli...
Erlotinib HCl
Product Description
Erlotinib HCl is an anti-cancer agent targeting epidermal growth factor receptor (EGFR) tyrosine kinase ATP binding sites, which are commonly overexpressed and sometimes mutated in a variety of cancers. Erlotinib prevents the formation of EGFR homodimers leading to suppression of signal transmittance and tumor growth inhibition. Additionally, erlotinib suppresses cyclin-dependent kinase 2 (Cdk2). It has been shown to be effective against non-small cell lung cancer and pancreatic cancer.
Product Specifications
Erlotinib HCl
Tarceva®
MOLECULAR BIOLOGY GRADE
Formula: C22H23N3O4
MW: 393.44 g/mol
Storage/Handling: Store at 2-8 °C. Product is soluble in acid (pH 2) at 0.4 mg/mL.
PubChem Chemical ID: 176870
Air shipments may require special packaging and a small additional box charge.
Product Specifications
| Catalog ID | E-270 |
|---|---|
| CAS # | 183321-74-6 |
| MW | 393.44 g/mol |
| Grade | MOLECULAR BIOLOGY GRADE |
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Technical Documentation
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C
Certificate of Analysis
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Safety Data Sheet
