trans-Aconitic acid (abbreviated TAA) is the trans isomer of Aconitic acid. As an antimicrobial agent trans-Aconitic acid is used as an antileishmanial to prevent L. donovani from transforming from amastigotes to promastigotes, thus inhibiting the reproduction of the bacteria. In synthesis, TAA allows for the crosslinking of carboxylic acids to create polyvinyl alcohol films that are water-soluble. Found in range grasses at varying concentrations, it inhibits the tricarboxylic acid cycle it may be partially responsible for nutritional disorders in grazing cattle.
MW: 174.11 g/mol
Storage/Handling: Store at 4°C. Protect from light.
PubChem Chemical ID: 444212