Furazolidone is a nitrofuran derivative antibiotic with antiprotozoal and antibacterial activity. It targets a wide variety of bacteria, including those responsible for gastrointestinal infections. It has also been used as a DNA cross-linking agent.
Furazolidone binds bacterial DNA, inhibiting monoamine oxidase (MAO). It induces cross-links leading to an increased rate of mutation or halted DNA replication.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
MOLECULAR BIOLOGY GRADE
MW: 225.16 g/mol
Storage/Handling: Store at 2-8°C.
This product is light sensitive.
PubChem Chemical ID: 5323714
|MOLECULAR BIOLOGY GRADE
|Store at 4°C. Protect from light.