Erythromycin ethylsuccinate is a macrolide antibiotic with a target spectrum similar to that of penicillin. It has shown high efficacy against Mycoplasma pneumoniae and Legionella pneumophila. Additionally, it has been used to study erythromycin-resistance bacteria, down-regulation of motilin receptors, and mutations on the omsA and firA genes. Erythromycin ethylsuccinate is freely soluble in organic solvents.
Macrolide antibiotics are composed of a macrocyclic lactone ring attached to one or more deoxy sugars. They inhibit bacterial protein synthesis by irreversibly binding the P site of the 50s ribosome, preventing peptide bond formation and translocation.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
MOLECULAR BIOLOGY GRADE
MW: 862.05 g/mol
Storage/Handling: Store in a dry and well-ventilated place. This product is light sensitive and soluble in most organic solvents.
PubChem Chemical ID: 443953
|Grade||MOLECULAR BIOLOGY GRADE|