CSF3 (G-CSF), Rat
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Rat Colony Stimulating Factor 3 (granulocyte)
Granulocyte Colony-Stimulating Factor, G-CSF
Colony Stimulating Factor 3 (CSF3), formerly called granulocyte colony stimulating factor (GCSF), is a pleiotropic cytokine. It is mainly produced by monocytes and macrophages upon activation by endotoxin, TNFα and IFNγ. Many cell types secreted this protein after LPS, IL1 or TNFα activation, including fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells. Various carcinoma cell lines and myeloblastic leukemia cells can express CSF3 constitutively. CSF3 is cytokine that acts in hematopoiesis by controlling the production, differentiation and function of two related white cell populations of the blood, the granulocytes and the monocytesmacrophages. In addition, it may function in some adhesion or recognition events at the cell surface.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
MW:~21.5 kDa (195 amino acids)
Purity:>97% by SDS-PAGE and HPLC analyses.
Biological Activity: Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using murine NFS-60 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0× 107 IU/mg.
Storage/Handling:Store desiccated at -20°C.
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
|Storage/Handling||Store desiccated at -20°C.|