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Product Description

Acalabrutinib (ACP-196) is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK), which is responsible for the maturation of B-cells. Its high selectivity to bind the residue Cys481 in the active site of BTK is a sought after feature for oncology research. Studies on mice and human cells demonstrate the high affinity of ACP-196 and its low affinity toward similar proteins in T-cell maturation.

Product Specifications

Formula: C26H23N7O2

MW: 465.51 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 71226662

Product Specifications

Catalog ID A-415
CAS # 1420477-60-6
MW 465.51 g/mol

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$12.99 Ground shipping (In continental US only.)

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