Cyclosporin B

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Product Description

The cyclosporins are a group of macrolide immunosuppressants isolated from fungi. They are researched for their use in prevention of post-transplant graft rejection. Their mechanism of action involves suppression of cytotoxic T-cell maturation and activity by binding lymphocyte protein cyclophilin. Cyclophilin and cyclosporin form a complex targeting calcineurin, which is responsible for activating T-lymphocytes. Additionally, the cyclosporins are researched for their ability to prevent damage to normal functioning cells in autoimmune disorders.

Cyclosporin B is soluble in DMSO and ethyl alcohol.

Product Specifications
Cyclosporin B

Formula: C61H109N11O12

MW: 1,188.58 g/mol

Storage/Handling: Store at 2-8°C. Soluble in DMSO and EtOH.

PubChem Chemical ID: 6450331

Product Specifications

Catalog ID C-942
CAS # 63775-95-1
MW 1188.58 g/mol

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

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$12.99 Ground shipping (In continental US only.)

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