Pyruvic acid is the simplest alpha-keto acid, and is considered to be key in several metabolic processes. Because pyruvate, which is the carboxylate ion of pyruvic acid, can be converted into carbohydrates, fatty acids or energy, it is a uniting intermediate compound and its fate depends on the organism and environment.
It is produced during glycolysis, and through the Krebs cycle (citric acid cycle), it supplies cells with energy. Two molecules of pyruvate are produced from one glucose molecule. Pyruvate is then converted into acetyl-coenzyme A used in the Krebs cycle.
In gluconeogenesis, pyruvic acid can be converted back into glucose or glycogen, and in environments with low oxygen, pyruvic acid is broken down anaerobically into lactic acid.
Clinically, the lactate-to-pyruvate ratio can assist in diagnosing mitochondrial respiratory chain disorders because the ratio is often, but not always elevated in these cases. There is also a lower ratio typically observed in inherited pyruvate metabolic disorders.
Pyruvic acid sodium salt
alpha-Ketopropionic acid sodium salt
MOLECULAR BIOLOGY GRADE
MW: 110.04 g/mol
Storage/Handling: Store at room temperature.
PubChem CID: 23662274
|MOLECULAR BIOLOGY GRADE
|Store at room temperature.