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Product Description

Enoxacin is a fluoroquinolone antibiotic compound that is markedly effective against gram negative bacteria. It has been used to study fluoroquinolone cross-resistence in Escehria coli, Pseudomonas aeruginosa and Staphylococcus aureus. Enoxacin is structurally related to nalidixic acid and inhibits DNA gyrase in bacteria.

Fluoroquinolones are a group of broad-spectrum antibiotics that inhibit DNA synthesis. These antibiotics prevent unwinding of double-stranded DNA by binding DNA gyrase or DNA topoisomerase. By preventing the formation of single-stranded DNA, fluoroquinolones inhibit bacterial replication.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Enoxacin sesquihydrate

Formula: C15H17FN4O3 ∙ 1.5 H2O

MW: 347.36 g/mol

Storage/Handling: Store desiccated at room temperature.

PubChem Chemical ID: 3229

Product Specifications

Catalog ID E-900
CAS # 74011-58-8
MW 347.36 g/mol

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

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