Teicoplanin

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Product Description

GoldBio Teicoplanin is for research use only!

Teicoplanin is a glycopeptide antibiotic isolated from Actinoplanes teichomyceticus. It is a mixture of several teicoplanins. Teicoplanin is effective against gram-positive bacteria resistant to β-lactam antibiotics. It has been effective against methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.

Teicoplanin works by inhibiting peptidoglycan synthesis and polymerization in two ways. One mechanism inhibits N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) from coming together to form the peptidoglycan backbone. Another mechanism prevents cross-linking between amino acid residues in the peptidoglycan chain, similarly to the mechanism of vancomycin.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Teicoplanin

MOLECULAR BIOLOGY GRADE

Formula: C88H97Cl2N9O33

MW: 1,879.66 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 16131923

Product Specifications

Catalog ID T-230
CAS # 61036-62-2
MW 1879.66 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.

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