Ampicillin (Sodium) 100 mg/mL Solution

Ampicillin sodium is a member of the extended-spectrum β-lactam family and similar in structure to penicillin. It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella. It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation. Ampicillin Sodium is freely soluble in water.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications
Sodium Ampicillin in H₂O
(100 mg/mL Premade Solution, 0.2 µm Sterile Filtered)

MOLECULAR BIOLOGY GRADE

Formula: NaC₁₆H₁₈N₃O₄S

MW: 371.39 g/mol

Storage/Handling: Store at -20°C

PubChem Chemical ID: 23663979