XCL1, Human

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Chemokine (C motif) Ligand 1 (XCL1)
Lymphotactin (LTN, LPTN)
Small Inducible Cytokine Subfamily C Member 1 (SCYC1)
Single Cysteine Motif 1 (SCM1, SCM1A)
Activation Induced T-Cell-Derived And Chemokine Related (ATAC)

XCL1 is a chemokine lacking the first and third conserved cysteine residues usually found in chemokines. It is expressed in thymic and peripheral blood CD8+ T-cells and in natural killer cells. Highest levels of expression are seen in spleen, thymus, small intestine, and peripheral blood leukocytes. XCL1 is chemotactic for natural killer cells and CD4+ and CD8+ T-cells. It assumes two distinct conformations, one of which has been shown to inhibit HIV-1 isolates. XCL1 is a ligand for XCR1 as well as the virus-encoded viroreceptor M3.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~10.2 kDa (92 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.

Storage/Handling: Store desiccated at -20°C.

HGNC: 10645

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM