Description
Tetracycline is a broad-spectrum antibiotic targeting gram-negative and gram-positive bacteria. It also displays toxicity against certain eukaryotic cells. Tetracycline is used in multidrug resistance studies and in cell culture applications as a selective agent. Additionally, it promotes expression of the P450 proteins.
Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited. Resistance to tetracycline arises from loss of cell wall permeability and the tetR gene.
TESTED AGAINST BOTH SENSITIVE AND RESISTANT CELLS.
Product Specifications
Tetracycline Hydrochloride
MOLECULAR BIOLOGY GRADE
Formula: C 22H24N2O8HCl
MW: 480.9 g/mol
Storage/Handling: Store desiccated at -20°C, and protect from light. Soluble in water.
PubChem Chemical ID: 5359252
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