Pyrazinamide is an anti-tubercular antibiotic. It is also used to study ways to prevent liver toxicity and in the formation of polymeric copper complexes.
Although the mechanism of action of pyrazinamide is not well understood, it is thought that upon entering a target cell, it is converted to pyrazinoic acid or POA. This conversion results in altered cellular permeability and decreased internal pH due to POA accumulation in the cytoplasm. This may inhibit fatty acid synthesis.
MOLECULAR BIOLOGY GRADE
MW: 123.11 g/mol
Storage/Handling: Store at 2-8°C.
Soluble in alcohol or aqueous solution.
PubChem Chemical ID: 1046
|MOLECULAR BIOLOGY GRADE
|Store at 4°C.