Lactitol is a disaccharide binding a beta-D-galactopyranose and D-glucitol to produce the sugar alcohol also known as Lactitol. It’s derived from lactose, a product of disaccharide’s glucose being reduced. It has been used as a laxative agent, excipient, and low-calorie artificial sweetener. Other characteristics of Lactitol display antibiotic and prebiotic activity.
Studies have demonstrated Lactitol decreases cholesterol metabolism and can treat liver diseases like hepatic encephalopathy. This function arises from the management of ammonia in the blood following cirrhotic damage to the liver. Revertant bacteria and aberrant cells were not seen to increase with the administration of Lactitol as a therapeutic substance, suggesting no mutagenicity.
Further properties increased bifidobacteria and lactobacilli after Lactitol consumption. One survey also recorded PYY and GLP-1 levels rising with ingestion of Lactitol. In a study on fecal flora, low dosage of Lactitol did not change pH; it also had no effect on the colonization of necessary anaerobes, aerobes or Enterobacteriaceae. These results promote Lactitol’s probiotic qualities.
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