Homocysteine is a cysteine homolog that differs by having an additional methylene bridge. It is often used in vitro as a reference to measure L-homocysteine in plasma in order to diagnose homocystinuria. This genetic disorder causes the body to be unable to process certain amino acids.
Homocysteine is biosynthesized from methionine through the intermediate S-adenosylmethionine. Homocysteine can then be converted to cysteine or back to methionine. The conversion to cysteine requires vitamin B6 as a cofactor while the conversion back to methionine requires vitamin B12. Increased levels of homocysteine in plasma can occur because of a vitamin B deficiency.
MOLECULAR BIOLOGY GRADE
MW: 135.19 g/mol
Color/Purity: White to off-white crystalline powder
Storage/Handling: Store in -20°C. Protect from light.
PubChem Chemical ID: 91552
|MOLECULAR BIOLOGY GRADE
|Store desiccated at -20°C. Protect from light.