Gramicidin is an antibiotic mixture of six antimicrobial polypeptides isolated from Bacillus aneurinolyticus. It targets the cell membrane of gram-positive bacteria and alters the cell membrane permeability. This leads to cell death. Gramicidin is not soluble in aqueous solution.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
MOLECULAR BIOLOGY GRADE
MW: 1,882.29 g/mol
Storage/Handling: Store at 2-8°C. Soluble in Methanol or Ethanol.
PubChem Chemical ID: 16130140
|Grade||MOLECULAR BIOLOGY GRADE|
|Storage/Handling||Store at 4°C.|