Fusidic acid is a fusidane antibiotic compound that exerts potent bacteriostatic effects toward gram positive bacteria. It is commonly implemented with bactericidal antibiotics such as rifampicin. Fusidic acid is an inhibitor of protein synthesis by disrupting amino acid transfer from tRNA to ribosomes.
Fusidic acid inhibits a GTPase called elongation factor G or translocase. Impeding translocase activity hidners movement of tRNA and mRNA through ribosomes. While predominant effects are bacteriostatic, higher concentrations will result in bacterial death.
MW: 516.71 g/mol
Storage/Handling: Store desiccated at 4°C.
PubChem Chemical ID: 300226
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