Fosfomycin sodium is a phosphoenolpyruvate analog antibiotic isolated from Streptomyces fradiae. It targets gram-positive and gram-negative bacteria, especially E. faecalis and E. coli. Fosfomycin concentrates in the bladder and kidney, decreasing nephrotoxicity and ototoxicity of anti-tumor agents containing platinum.
It functions by inhibiting cell wall synthesis by inactivating the MurA enzyme. Fosfomycin sodium is freely soluble in aqueous solution.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Phosphomycin Disodium Salt
MOLECULAR BIOLOGY GRADE
MW: 182.02 g/mol
Storage/Handling: Store at 2-8°C.
PubChem Chemical ID: 73491
|MOLECULAR BIOLOGY GRADE
|Store at 4°C.