GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Human Fibroblast Growth Factor 23
FGF23 is a member of the Fibroblast Growth Factor family of proteins. In the FGF family, FGF23 is most closely associated with FGF15/19 and FGF21 (see additional information). FGF23 shares 71% homology with mouse Fgf23 at the amino acid level. FGF23 is produced by osteocytes and osteoblasts in response to high circulating phosphate levels, elevated parathyroid hormone, and circulatory volume loading. It functions as an endocrine phosphatonin by suppressing circulating phosphate levels. FGF23 interaction with renal proximal tubular epithelium decreases the renal resorption of phosphate by down regulating phosphate transporters and by suppressing vitamin D production. It also decreases the intestinal absorption of phosphate.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~15.5 kDa (134 amino acid)
Purity: >97% by SDS-PAGE and HPLC analyses
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
Note: 1000 µg volume may be delivered in multiple containers.
|Storage/Handling||Store desiccated at -20°C.|
Relative mitogenic activity of FGFs against FGF Receptors compared to FGF1 (aFGF).
HuFGF23 Product Description, Amino Acid Sequence, Reconstitution and Storage Conditions