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EGF, EGFRs and their Role in Cancer
Ever since the beginning of our awareness of growth factors in the early 1960’s by Stanley Cohen and...
EGF, Rat
Product Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Rat Epidermal Growth Factor
EGF
HMGF (Human Milk Growth Factor)
PGF (Prostatic Growth Factor)
EGF (Epidermal Growth Factor) is a family of growth factors that are derived from membrane-anchored precursors. The family is characterized by the presence of at least one “EGF-like domain” (characterized by the presence of three disulfide bonds, formed from 6 conserved cysteine residues) in their extracellular domain. EGF was originally discovered as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition and stunting of growth when injected into newborn mice. Additionally, EGF has been shown to inhibit gastric secretion, is involved in wound healing and signals through a receptor known as c-erbB (a class I tyrosine kinase receptor).
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~6.2 kDa (54 amino acid)
Purity: >97% by SDS-PAGE and HPLC analyses
Storage/Handling: Store desiccated at -20°C.
Rat Genome Database ID: 2542
NOT FOR HUMAN USE!
Cross-species homology
Percent Similarity
| HuEGF | MuEGF | RtEGF | |
| HuEGF | *** | 69.8 | 68.5 |
| MuEGF | *** | *** | 75.9 |
| RtEGF | *** | *** | *** |
Additional resources for this protein may be found at:
OMIM
Note: 1000 µg volume may be delivered in multiple containers.
Product Specifications
| Catalog ID | 1550-04 |
|---|---|
| MW | ~6.2 kDa |
| Storage/Handling | Store desiccated at -20°C. |
Technical Documentation
P
Protocol
O
Other
C
Certificate of Analysis
S
Safety Data Sheet
