CXCL13, Human

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Product Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Chemokine (C-X-C motif) Ligand 13 (CXCL13)
B-Lymphocyte Chemoattractant (BLC)
Small Inducible Cytokine Subfamily B Member 13 (SCYB13)
Angie, Angie2
B Cell-Attracting Chemokine 1 (BCA1)

CXCL13 is a CXC chemokine lacking the ELR motif. It is expressed highest in liver tissue, followed by spleen, lymph nodes, appendix, and stomach. It is a ligand for CXCR5 and is selectively chemotactic for B lymphocytes. CXCL13 plays an essential role in the development of lymph nodes and the organization of B cells within lymphoid follicles, but its expression is downregulated within lymphoid tissues by IFN-gamma during immune responses. CXCL13 induces B cells to upregulate lymphotoxin alpha-1-beta-2, leading to CXCL13 expression and creating a positive feedback loop essential for follicular dendritic cell development and homeostasis.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~10.3 kDa (87 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human B cells is in a concentration range of 1-10 ng/ml.

Storage/Handling: Store desiccated at -20°C.

HGNC: 10639


Additional resources for this protein may be found at:

Product Specifications

Catalog ID 2110-13
MW ~10.3 kDa
Storage/Handling Store desiccated at -20°C.

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$12.99 Ground shipping (In continental US only.)

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