Colchicine is an alkaloid isolated from Colchicum autumnale and other Colchica species. It is an antimitotic agent useful against various cancer cell lines. Colchicine disrupts microtubules and can be used to induce tetraploidy in plant cells. It is an activator of the JNK/SAPK signaling pathway and used to select for cells containing MDCK (NBL-2) resistance. Colchicine’s antimitotic properties are more effective against cancer cells due to their increased mitotic rate compared to that of healthy cells. Colchicine is useful in cell division studies.
MOLECULAR BIOLOGY GRADE
MW: 399.44 g/mol
Storage/Handling: Store at 2-8 °C.
This product is light sensitive.
PubChem Chemical ID: 6167
Air shipments may require special packaging and a small additional box charge.
|Grade||MOLECULAR BIOLOGY GRADE|
|Storage/Handling||Store at 4°C.|