Capreomycin sulfate is a cyclic peptide antibiotic often classified with the aminoglycoside antibiotics. It is used as a second line antibiotic for studying multidrug resistant tuberculosis. Capreomycin is primarily used against Mycobacterium tuberculosis.
Although the mechanism of action of capreomycin is not well understood, it is thought to exhibit a mechanism similar to aminoglycosides, which bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, inhibiting protein synthesis.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Formula: C24H42N14O8 • H2SO4
MW: 752.76 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 22836615
|Storage/Handling||Store desiccated at -20°C.|