Bergapten

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Product Description

Bergapten or 5-Methoxypsoralen is a linear 5-methoxyfurocoumarin with photosensitizing effects occurring as a natural metabolite in plants like anise and celery. Concentrated amounts are found in bergamot and other citrus essential oils, causing phototoxicity. Its photochemical properties have led to application as a photonic material, heptatoprotective agent and skin pharmaceutical. It manifests as a crystalline solid and is stable, combustible and incompatible with strong oxidizing agents.

Bergapten has been studied as an antitumor agent in cancer research. In combination with UV light irradiation, Bergapten has been used to manage diseases like psoriasis and vitiligo and can also inhibit hepatocellular carcinoma cell proliferation. As a selective potassium-channel blocker, it reduces K-permeability at nodes of Ranvier, possibly producing fasciculation and cramps. Exposure to the corrosive chemical has demonstrated negative effects on health including erythema, dermatitis, hyperpigmentation and epitheliomas.

Product Specifications
Bergapten
Heraclin
5-Methoxypsoralen
4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one
4-Methoxy-7H-furo[3,2-g]chromen-7-one

Formula: C12H8O4

MW: 216.19 g/mol

Storage/Handling: Store under inert gas at 4°C. Protect from light.

PubChem Chemical ID: 2355

Product Specifications

Catalog ID B-155
CAS # 484-20-8
MW 216.19 g/mol

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