IL13, Rat (113 a.a.)

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Product Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Interleukin-13
Interleukin 13

Interleukin-13 (IL13) is expressed by the IL13 gene and secreted by many cell types, especially helper T-cells type 2 (Th2). The high solution form of IL13 is reported to be a monomer with two internal disulfide bonds that contribute to a bundled four α-helix configuration. Targeted deletion of IL13 in mice resulted in impaired Th2-cell development, and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and inhibits the expression of inflammatory cytokines such as IL1β, TNF-α, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation, and to induce isotype switching that results in an increased production of IgE. Mature rat IL13 shares 60%, 76%, and 60% amino acid sequence identity with human, mouse, and rhesus IL13, respectively.

Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~12.3 kDa (113 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.


Rat Genome Database ID: 68949

Cross-species Homology

Percent Similarity:

HuIL13 MuIL13 RtIL13
HuIL13 *** 57.0 60.2
MuIL13 *** *** 76.1
RtIL13 *** *** ***

Additional resources for this protein may be found at:

Product Specifications

Catalog ID 1510-13B
MW ~12.3 kDa
Storage/Handling Store desiccated at -20°C.

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$12.99 Ground shipping (In continental US only.)

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