2-Hydroxypalmitic acid

2-Hydroxypalmitic acid is a 2-hydroxy fatty acid consisting of a C16 chain with a hydroxyl substituent at position 2. This metabolite is considered a saturated long-chain fatty acid due to its straight chain. Consequently, it has potential as an anti-inflammatory agent, neuroprotection and defense against bacteria and cancer. 2-Hydroxypalmitic acid can also be used as a surfactant.

Sphingomyelin in the epidermis of murines have displayed the alpha-hydroxypalmitic acid in TLC bands. When murine papillomas were measured for the substance, it was diminished in SENCAR and SSIN phingomyelin, implying there is a selective process in tumorigenesis which causes hydrolysis of sphingomyelin containing such fatty acids.

In yeast, 2-Hydroxypalmitic acid was seen to increase when fumonisin B1, a compound similar to sphingolipds which enhances yeast 2-hydroxy fatty acids, was added to the growth medium.

Product Specifications
2-Hydroxypalmitic acid
DL-alpha-Hydroxypalmitic acid
2-Hydroxyhexadecanoic acid
2-Hydroxy-hexadecylcarboxylic acid
(+)-15S-hydroxy-hexadecanoic acid

Formula: C₁₆H₃₂O₃

MW: 272.42 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 92836