Bleomycin A5 hydrochloride

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Product Description

Bleomycin A5 hydrochloride is a compound part of the glycopeptide antibiotic family. It is currently used in oncology research for its strong stimulatory and inhibitory effects. Bleomycin A5 greatly reduces telomerase activity, hindering the proliferation of malignant cells. It has also been shown to induce in vivo fibrosis and inflammation by generating peroxynitrites, a strong oxidizing agent.

Bleomycin A5 stimulates downstream apoptosis by increasing cysteine-aspartic acid protease-3 (caspase-3) activity, tumor protein 53 (p53) production and transforming growth factor beta 1 (TGF-beta 1) formation. These proteins induce apoptosis directly or indirectly by halting cell growth.

Product Specifications
Bleomycin A5 hydrochloride
1-Bleomycinoic acid hydrochloride

Formula: C57H89N19O21S2

MW: 1477.02 g/mol

Storage/Handling: Store desiccated at 4°C.

PubChem Chemical ID: 84058

Product Specifications

Catalog ID B-405
CAS # 55658-47-4
MW 1477.02 g/mol

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

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$12.99 Ground shipping (In continental US only.)

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