Ethambutol DiHCl is a hydrochloride salt form of an ethylenediamine derivative that is used as an anti-mycobiotic. It has been used for studying multidrug resistance in Mycobacterium tuberculosis and to investigate effective antibiotic combinations for ethambutol DiHCl.
It has been used for bacterial selection and its bactericidal mechanism is not well understood. Some research has found ethambutol DiHCl to inhibit mycolic acid transport into mycobacterial cell walls. Mycolic acid is a fatty acid chain that is a key component of mycobacterium’s resistance to many antibiotics and harsh conditions.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Formula: C10H24N2O2 ∙ 2HCl
MW: 277.23 g/mol
Storage/Handling: Store at room temperature.
PubChem Chemical ID: 14051
|Storage/Handling||Store at room temperature.|