object(anvilstl\commercio\models\Category)#413 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(66) ["root"]=> int(1) ["lft"]=> int(100) ["rgt"]=> int(131) ["level"]=> int(3) ["name"]=> string(11) "Antibiotics" ["url_name"]=> string(11) "antibiotics" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(701) "

Gold Biotechnology offers more than 200 unique antibiotic agents for use in a wide variety of cell culture, microbiology and molecular biology applications. Antibiotic agents are often clinically used to inhibit bacterial growth or kill bacteria as selection markers in agar or liquid media. The first commercially available antibiotics were developed in the 1930s, starting with the sulfonamides in 1932 and exploded later with the discovery of penicillin in 1942. Gold Biotechnology’s antibiotics cover 14 classes, including aminoglycosides, carbapenems, macrolides, penicillins, quinolones, sulfonamides and tetracyclines, as well as multiple generations of cephalosporin antibiotics.

" ["hide"]=> int(0) ["third_party_id"]=> int(36) ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(146) "GoldBio carries more than 150 quality research antibiotics, including a variety of aminoglycosides, glycopeptides, cephalosporins and penicillins." 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object(anvilstl\commercio\models\Category)#440 (15) { ["featured_image_urls"]=> array(0) { } ["featured_image"]=> array(0) { } ["banner_image_urls"]=> array(0) { } ["productCount"]=> NULL ["_attributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(69) ["root"]=> int(1) ["lft"]=> int(107) ["rgt"]=> int(108) ["level"]=> int(4) ["name"]=> string(14) "Cephalosporins" ["url_name"]=> string(14) "cephalosporins" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(894) "Celphalosporins are a class of β-lactam antibiotics. β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes that catalyze a pentaglycine cross-link between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine cross-link, the integrity of the cell wall is severely compromised, and ultimately leads to cell lysis and death. First generation cephalosporins are typically active against gram-positive bacteria with successive generations having an increasingly broadened activity against gram-negative bacteria. GoldBio’s catalog of cephalosporins contains antibiotics across four generations of cephalosporin activity. Cephalosporins are historically inactive against Listeria, Atypicals (including Mycoplasma and Chlamydia), MRSA, and Enterococci.
" ["hide"]=> int(0) ["third_party_id"]=> int(257) ["featured_image_id"]=> int(0) ["banner_image_id"]=> int(0) ["meta_description"]=> string(157) "GoldBio’s cephalosporins cover four generations of cephalosporin activity. These successive generations show broad activity against gram-negative bacteria." ["meta_keywords"]=> string(0) "" ["root_sort"]=> int(0) ["type"]=> string(7) "product" ["condition_type"]=> int(1) ["condition_match_type"]=> int(1) ["sort_type"]=> int(1) ["items_per_page"]=> int(25) ["color"]=> NULL } ["_oldAttributes":"yii\db\BaseActiveRecord":private]=> array(23) { ["id"]=> int(69) ["root"]=> int(1) ["lft"]=> int(107) ["rgt"]=> int(108) ["level"]=> int(4) ["name"]=> string(14) "Cephalosporins" ["url_name"]=> string(14) "cephalosporins" ["title"]=> NULL ["short_description"]=> string(0) "" ["long_description"]=> string(894) "Celphalosporins are a class of β-lactam antibiotics. β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes that catalyze a pentaglycine cross-link between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine cross-link, the integrity of the cell wall is severely compromised, and ultimately leads to cell lysis and death. First generation cephalosporins are typically active against gram-positive bacteria with successive generations having an increasingly broadened activity against gram-negative bacteria. GoldBio’s catalog of cephalosporins contains antibiotics across four generations of cephalosporin activity. Cephalosporins are historically inactive against Listeria, Atypicals (including Mycoplasma and Chlamydia), MRSA, and Enterococci.
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Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.

GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.

Antibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.

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Cefoxitin

Name: Cefoxitin
SKU: C-960
Availability: InStock

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Product Description

Cefoxitin is a cephamycin antibiotic grouped with the second generation cephalosporins. It is effective against gram-positive and gram-negative bacteria and is especially effective against anaerobic bacteria. Cefoxitin is resistant to degradation by β-lactamases.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Cefoxitin

MOLECULAR BIOLOGY GRADE

Formula: C₁₆H₁₇N₃O₇S₂

MW: 427.45 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 441199

Product Specifications

Catalog ID	C-960
CAS #	35607-66-0
MW	427.45 g/mol
Grade	MOLECULAR BIOLOGY GRADE
Storage/Handling	Store at -20°C.

Technical Documentation

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O Other

C Certificate of Analysis

S Safety Data Sheet

COA - C-960

Certificate of Analysis - Cefoxitin

SDS (MSDS) - Cefoxitin

Safety Data Sheet

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