Cephapirin benzathine

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Product Description

Cephapirin benzathine is a benzathine salt form of a first generation cephalosporin antibiotic. Cephapirin benzathine has a wide range of activity against gram negative and gram positive bacteria. It has also been used as an antifungal in animals infected with Candida albicans. Benzathine salt has been shown to prolong the duration of antibiotic activity in cephapirin benzathine.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Cephapirin benzathine

Formula: C34H34N6O12S4 ∙ C16H20N2

MW: 1087.27 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 167441


Product Specifications

Catalog ID C-745
CAS # 97468-37-6
MW 1087.27 g/mol

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