Cefozopran HCl
Product Description
Cefozopran is a fourth generation cephalosporin antibiotic effective against a variety of gram-negative and gram-positive organisms, including Pseudomonas aeruginosa. It is effective against MRSA when combined with antibiotics such as vancomycin and teicoplanin. Cefozopran HCl is soluble in DMSO and water.
Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Product Specifications
Cefozopran HCl
Cefozopran Hydrochloride
MOLECULAR BIOLOGY GRADE
Formula: C19H17N9O5S2 ∙ HCl
MW: 551.99 g/mol
Storage/Handling: Store at 2-8 °C.
PubChem Chem ID: 9690120
Product Specifications
Catalog ID | C-690 |
---|---|
CAS # | 113359-04-9 |
MW | 551.99 g/mol |
Grade | MOLECULAR BIOLOGY GRADE |