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Hygromycin B

Catalog ID Size Pricing
H-270-1 1 g $68.00 $54.40
H-270-2-1 2 x 1 g $127.00 $101.60
H-270-2.5 2.5 g $161.00 $128.80
H-270-5 5 g $281.00 $224.80
H-270-5-1 5 x 1 g $305.00 $244.00
H-270-10 10 g $506.00 $404.80
H-270-10-1 10 x 1 g $518.00 $414.40

Description

Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It is commonly used to study protein synthesis. Aside from its efficacy against bacteria, fungi, and higher eukaryotic cells, hygromycin B is also an antiviral agent inhibiting translation upon selectively entering cells made permeable due to viral infection. It works as a standard selection antibiotic in gene experiments, especially for selection of hygromycin resistance gene transformed cells.

Product Specifications

Catalog ID H-270
CAS # 31282-04-9
MW 527.52 g/mol
Storage/Handling Store desiccated at -20°C.
UN Number 3462
Item Class 6.1
Group Number I
Hygromycin Product Information

Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It is commonly used to study protein synthesis. It works as a standard selection antibiotic in gene experiments, especially for selection of hygromycin resistance gene transformed cells. Aside from its efficacy against bacteria, fungi, and higher eukaryotic cells, hygromycin B is also an antiviral agent inhibiting translation upon selectively entering cells made permeable due to viral infection.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.



SPECIFICATIONS

Hygromycin B

Formula: C20H37N3O13

MW: 527.52 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 35766

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